But . . . will Americans have to go overseas, or at least north (or south!) of the border to find a clinic legally able to create these implants?

Stefan, I do not expect so. Why would you expect that? I expect to see this company either open clinics in the US or license the technology to a US company.

"Why would you expect that?"

It involves the use of stem cells.

The article notes:

"Doctors take stem cells from the patient"

But have we perfected fundamentalist-friendly techniques to turn adult cells into stem cells?

Stefan, adult stem cells are already stem cells. They are already used in some forms of treatment successfully. For many applications there is no need to revert adult stem cells to the embryonic state.

Turn about is fair play:

Dental pulp used to treat Parkinson's Disease:

http://www.sciencedaily.com/releases/2004/05/040505065427.htm

Stephan, surely you can see through the use of dead baby cells, which could be your dead relatives for mass market use, is ONLY a front for keeping the abortion business in business, as stem cells, which always are undifferentiated cells that can be coaxed to grow like tissue from similar tissues are far more reliable and safer than dead fetus babies' cells.

I have been very interested to read all the research taking placing attempting to grow replacement teeth in the gum via stem cells.

I should be very interested to know if volunteers for this research are required, and if so would happily supply all information required as necessary to determine my suitability as a volunteer. My telephone contact is 01895 822141.

Hoping to hear further from you.

Iris Micks

I am also very interested in your research and would be more than willing to volunteer to be involved with your work in this field. I am a forty year old male with a few teeth missing It would be a dream come true for peple like my self to be able to grow new teeth. I can also be contacted on. 07941 243153

I am also interested in becoming a volunteer for teeth regrowth, I am 40 years old and lost all my teeth 15 years ago. I just had a new set of dentures made and payed alot for something that I aboslutley hate.

I am also interested in becoming a volunteer for teeth regrowth, I am 56 years old and lost all my teeth 26 years ago. I also just had a new set of dentures made and paid £500 for private treatment. I hate them - they are obviously false. I have been considering dental implants.

How could an individual like myself become financially invested in such a company. I am a dental student and think the potential for this to explode into a fantastic opportunity will come very quickly.

Regards.

Fantastic idea doctor sharpe.My name is Paul Gibson,i am 35 years of age and in good health.Whislt having a an exciting rugby history it has left me with major teeth problems.I have been referred to manchester dental hospital due to the severity of my case.I would like to put my self forward as a volounteer for teeth re-growth if that is at all possible.
Regards P.G.Gibson

What are the bans on this practice? Why you have not started yet on human being??
When do you expect will be available for everybody????
Please reply because I need your sensational discovery.
Bye
Jonathan

All'eta' di 43 anni porto gia' una protesi totale dell'arcata superiore mentre l'arcata inferiore è composta da soli 6 denti e tutti con carie avanzata.Vorrei sottopormi alla terapia rigenerativa per far ricrescere i denti .Siete a conoscenza se in Italia cercano volontari per sottoporsi a questa nuova scoperta? Grazie

I would be very interested to be a volunteer for teeth regrowth project. I am 51 and in very good health, however I have gum disease and during the past three years, my back teeth (molars) had to be extracted one after the other because they were loose. Losing teeth has been devastating for me because I work in an industry where appearance is important.

I hope you put me in your database for the above - and my best wishes for the research team of Professor Paul Sharpe for this research and any other research - Hope you succeed!!

Hello I have contacted a dentist who said that your new technique is science fiction and that if we lose the teeth due to bone missing they will never regrow. Please CONFIRM IF IT IS TRUE OR NOT THANK YOU

When I was a teen I had some molars taking out making the back ones to move forward. This had cause me to have braces put in two years ago. I just recently had my braces out to undergo surgery for implants, I definitely prefer regrow teeth instead. I wish I could make a choice and try this method if it was available soon.

A true turn in the absolute right direction for dentistry! Hats off to you. I too, am very interested in this technology and eventual paradigm shift in dental thinking. There's no dentistry like NO dentistry . . . I would love to practice dentistry where I never have to pick up a drill again in my life . . . . godspeed!
aaroN

Well, I have a couple comments. First, there seem to be a lot of people here who think that Professor Sharpe was actually part of the conversation. He was mentioned in the article posted by Randall Parker, but I think some of you misinterpreted that he was the one mediating this discussion. At best, you could follow the links Randall provided to both Odontis, the company, as well as Professor Sharpe.

As for Jonathan's comment:
"Hello I have contacted a dentist who said that your new technique is science fiction and that if we lose the teeth due to bone missing they will never regrow. Please CONFIRM IF IT IS TRUE OR NOT THANK YOU"

It is not science fiction. It has already been done in rats (or was it mice?). If you really do care about this issue, you can do some research here and at other sites that discuss stem cell research, such as the Longevity Meme or BioMed Central. It shouldn't be too hard to find articles on those sites that cite the actual research studies that proved this is possible in rodents. And if it's possible in rodents, then you can't say that it's impossible in humans, even if it might be harder.

Not that I blame your dentist. I thought this was impossible two months ago. When I saw a prediction that we would be able to grow new teeth with stem cells by the end of the decade, I began to think about it more. But when I thought about it, it sounded too far-fetched to be something we could do in less than 20 years. Science just doesn't move that fast! So imagine my surprise when I found out it has already been done in animal studies! (On a side note, I was even more surprised to find out that Parkinson's disease has been cured in mice using stem cell therapies. I don't know what the success rate was, because I haven't seen the study, but it's surprising nonetheless).

A big theme at this website is that technology is not just advancing fast, it's advancing faster than most of us truly appreciate, and it continues to get faster, faster. The rate of progress in science is increasing exponentially. It's mind boggling to think about how fast technology is advancing. If only the politics could be voted out of the way, we'd be moving even faster!

Anita Hinke
Preysingstr. 46
81667 München
Tel. 0049/89/4483710

Dear Sir,

i´m sure that I´m the millionst person who offer her volunteer for your experiment. I´ve to decide to make a Implantation which i`dont like to do. i would like to try another way. For the case that all other volunteers are dispappeared you can call me and I will come immeadetly. (Sorry for my Englisch)

Yours faithfully
Anita Hinke

I am also interested in becoming a volunteer, I am 37yrs old and am about to loose my teeth due to gingivitis. I am otherwise a healthy male, who would love a cance to start again and do things right this time, one more thing, any chance of growing more hair?

Can't wait...well, I really will very patiently await the availability of "home grown" new teeth.

My very best friend, Siskiyou, a malamute dog, was shot and killed when we lived in Hawaii. Contrary to the sweet touristy images of Hawaii, there are some very violent people living in the rural areas there. When I confronted the person who did this he broke my jaw, broke my nose and knocked out most of my teeth...he's a huge guy way over 2X my size.
Yes, I went to the nearest police, but found out most of them were related (77th cousins or some such), and it was my word against his. Then too I was a mainlander, only recently retired-to Hawaii and he is a "local".

So when we (Siskiyou's "wife, Sacajahwea, and her children, and their children, 3 generations of malamutes all total) moved back to the continental USA I dug-up Siskiyou's bones, cleaned them off and carried them with us...leave no one behind.

My jaw's healed, my nose, well it's sort'a healed, but my heart is permanently broken...Siskiyou saved my life once when we were caught-out in a freak snow storm; "Sis" let me hold-on-to his tail as he guided us the +3 miles we had to trek through Mt. Hood National Forest in the Columbia Gorge, Oregon to get back to the truck. Then there was the 5 Japanese tourists he found. They had been lost in the Columbia Gorge for 2 days/nights when he sniffed them out. And there was the mother and her two young children out for a day hike in the Gorge who got lost (lots of trails but the trail marker signs are great "prizes" for folk who collect such things, so most of the trails are unmarked and if you're not familiar with the area easy to get turned-around or lost in), Sis found them as well.

But this is about new teeth, not way-too-soon-removed from life companion animals. Get'n some teeth will allow my face to smile again, though my heart may never.

I have some fears relating to complete regrowth of the teeth: The study I read (in Scientific America) said the final size of the new grown tooth was quite small, I am not sure if there was a reason for it or not, it was not told in the SA. I fear that complete regrowth of teeth will not be possible, at least for those with dead and shriveled nerves, in that I don't know of many studies done on succesful regrowth of nervine and sheath. Perhaps though, a person could have a special surgery done when removing a tooth so that the implanted stem cell touched the nerve to facilitate connection of the pulpine nerve.

As I said, it is highly unlikely that regrowth of the nerve can be induced, especially if the cell transplant is several years after death of said nerve. However, it is possible that regrowth of the nerve will occur, in this case a study should be done on programmed nerve stem cells for direct injection into severed spinal nerves -associated with paralysis- for regrowth of the nerve. Perhaps full paralysis can also be cured quickly!

Hey Guys..

I have personally spoken to Dr Paul Sharpe & Dr Mary Macdougall (Her team first discovered the potentail of tooth regeneration 20 yrs ago, Univesity of Texas, San Antonio).

Dr Sharpe mentioned he has more than 1000 volunteers at present. We could all just pray & cheer these researchers. I suggest we all send some donation to Dr. Sharpe (even $5 or $10 will help).

King's College London,
Strand
London
WC2R 2LS
England, UK
Email: paul.sharpe@kcl.ac.uk

Like all of you here, I too had tragic problem in England, with 2 of my upper-front teeth when I was 17. I had perfect set of teeth, smile & looks otherwise. Because of the pain & agony, I had to quit law school after a year & then quit medical schools after 3 years.

I have been praying for 12 years for some miracle cure. Please do whatever you could to lead these researcher. Today`s miracle is tommorrows cure/remedy.

There are 5 major japanese research institutes are working towards growing tooth via stem cells. Japanese are hoping to ship tooth-germ to USA by 2007. Forsyth institute/Harvard dental school too. But there are a lot of restriction on stem cell research in USA. Harvard is working with some Brazilian resaerch center.

So there are a lot of hope & just believe in the medical mystery. They are able to clone a human genetically. Therefore, growing tooth should be possible. Sharks replace their teeth every 2 weeks. We replace once .. there must be a something happening within our system to regrow tooth 2nd time. That genetic marker(embryonic stem cells) is so important to identify. I believe Dr Sharpe has identified that marker.

As for the size/shape of the teeth also controlled by genetic signalling. Dr Sharpe is working on that project currently. The reason I know this all is because I have been thing about going into do a research/PhD in this area.

Thanks for reading..

regards

Shahana

I have 4 teeth left on my upper gum and two missing on bottom, one my front tooth.I cannot wear my top plate as I constantly feel sick.My problems started when I fell off my bicycle and broke my two front upper teeth at the age of 10. Can you help. I am willing to take part in any experiment.

Yours sincerely

Margaret Boyd

Does anyone wear partial denture for only two upper-front teeth? If so .. could you let me know how does that work? Does it cause problem speaking? Where does it connect?

Thanks

Shahana

I came across this info tonight and got all kinds of excited. I was in an auto accident and as a result of the medication and treatment. I lost all but ten of my teeth, six of them being my front top. I have since then struggled with partials my dentist fits and has made for me and they are horrible...they look good but are awfully uncomfortable and do not work. They leave me with all kinds of sores, I have a mouthful of goop all the time in order to keep them anchored, and I cannot speak too well still. Unfortunately, I have not the finances to pay to have my teeth umplanted into the gums surgically, but have wanted to look into the possibility of having it done. My dentist has come to the conclusion I may be one of the very few he needs to send to a specialist and I am dreading that also. I would be exstatic at the opportunity to be a subject for this procedure, and would welcome the opportunity to see if I could get another set of teeth, especially since the reason I do not have any now is not my fault, and I had beautiful teeth before the accident. Is there any way I can contact someone to find out about this further and see if there is a chance of having this done? It certainly cannot be any more of a disaster than the two sets of partials I have already had made. Where can I go to look into this further? I have spent four visits to the dentist in tears at all I have to go through and this would be a real answer to prayer for me. I live in Charlotte, North Carolina, United States.

Hi Loretta,

Hi. I saw your message on the futurepundit site. I am so sorry about your accident. If you don`t mind .. How old are you now?

The tooth-regrow procedure is still at research stage .. the experiement was successful in other animals like rats, still untested in human. It may take 10-15 years before any success in human. If we are lucky maybe in 5 years.. will see some results. Still remains a mystery if it will work in human or not.

But I suggest you see a few reputable dentist before you decide to do anything .. especially "Implant". You could search on "google" or "yahoo" about cosmetic dentist`s in your area.

Also do some research on "tooth implants". It`s a difficult procedure. The procedure requires first to impant "screw" in your jaw (like the ones we hang paintings). Then leave the screws for 6-9 months to adjust/tighten in your jaw. It could be unpleasent. Lifetime for implants are about 10-15 years.

Implants are OK for 1 or 2 tooth .. but a whole set of 10 or 12 will be tough.

Additionally, if the scientist are able to regrow tooth genetically .. you will have to have good jaw-bone in order to hope for any sucessful regrow.

Alternate thing you could do is remove the remaining ten-teeth & wear a full set of denture .. there will be much less pain & your speech will be better.
My mother-in-law lost all her teeth at age 30 & she is now 60 .. she has been wearing full-dentures ever since.

What matters that you are not in pain & could lead a comfortable life. There are a lot of infection could be caused by multiple-implants.
You have to weigh a lot of issues. I am NOT trying to scare you at all. Just thinking about the most effective or least painful method.

Do see at least 3 dentist for opinion before you decide to do anything further.

Best wishes

Shahana

Hello
the possibiliy to regrow teeth must be found outside the dentists area.
We have not to waste our finances.
It must become a natural process, by changing our ADN.
It must be a global process involving an inner change.

An alchimist told me that in one ancien tibetan medicine book it is named the herb
that has the power to regrow teeth, difficult to find it now, but we can search
I red that some aborygen people have one similar too for the same purpose.

There are people in the Pacific zone with a third dentition.
In nature it is possible.
It is known that some buddist monks had a new set of teeth.

If you want to try a different way too you can read and patecipate to this search:

http://www.merkabaweb.net/forum/topic.asp?TOPIC_ID=61&FORUM_ID=19&CAT_ID=3&Topic_Title=regeneration

The website is www.merkabaweb.net

all the best
miraluce

I'm a young girl of 14 years. I was born in Sicily and I live there. When I was born I had all my milk theet but when I lose them, around the tenth year, no theet was growing. The rays I have done says that no roots are present. I want to know more about your research, please write back. I want to have the possibility to regrowe my theet.

Best wishes IVANA

Hello Ivana ,
i wrote above the url of the forum where you can find some suggestions...
It is good to collaborate, to exchange what someone has found.
The search is the search, it is not a discovering.
You can't find the stuff ready.
To want is the fist step but you have to search and to act.

I think that in your case some trauma has caused the inibition of the process .
I suggest you to work in bioenergetic therapyo or
in thr perceptible breathing in order to dissolve the trauma.

http://www.transformationetsouffle.com/t-e-s.pdf

http://www.breathexperience.com

To give the body what it is necessary
you can approch the ayurvedic medicine.
The two things together,

No dentist for that.
wishes

Please use me as your test patient. I can not afford implants and I want to be able to bite into a sandwich again someday. I can't even smile anymore at my poor children because I am so embarrassed by my poor smile.

I willfully want to participate, and am desperate for a response, please reply to: mullson@yahoo.com

Thank you.

This is wonderful science...a boon to hunmanity! I would love to be added to your list of volunteers if at all possible and /or mecessary to facilitate this procedure. thanks so much for all you are doing.

i can only admire the people behind the technology,

whether it be falling off a bike to a car crash, losing teeth has a vast effect on peoples lives. it can ruin a persons self esteem and confidence, obviously this technology will change lives.

i lost three of my top teeth when attacked late at night. it took 4 months of treatment and best part of £1000 to fix.
although they look very good under the circumstances they still arent the 'the real thing'

The slightest ray of hope gives humans a reason to struggle for survival. So be positive look after your remaning teeth and gums, don't go into drastic measures of implants as it may permanently reduce your options of using any future medical breakthrough. 'Ayurveda' is beyond doubt the oldest and most researched and successful therepy of its times. It was developed in ancient India and has scriptures on detailed medical procedures (even surgery which was pioneered by Sushuruta ages before it was even thought of by the modern world). But don't be fooled by quaks. If you can get hold of some genuine dental ayurvedic medicine it will help in maintianing what ever you are left with in your mouth. As for getting new teeth by this technique, It won't be possible as the poineers of this medicine have long been dead, the scriptirures are in Sanskrit the vedic books of the Hindu's and there is not that initiative or resources going into research in this field. Moreover earth and plants have evolved over a period of years and many herbal species have become extinct. So good luck to the researchers and till then good dental health try to salvage whatver your have with healthy eating practises.

Please read links below. Other research & development is underway to regrow tooth .. by "calcium phosphate" which is what found mostly in teeth & bone.

http://www.futurepundit.com/archives/001356.html
http://www.ada.org/ada/prod/adaf/paffenbarger/prog_bioactive.asp

Hello there! Gee, I see I am not the "only one" doing research on this subject for personal reasons too! I too would like to "volunteer" but think this web-site is not for signing up?? If it is please let m know! I too have many bad teeth, it is like a bad dream one wants to wake from. I hope all of us here are among the first to be healed! please keep me on any list this site may be associated with along with the rest of the good people here. Thank you! :) penowheel@hotmail.com

Take care, & God-speed too!! :)
Peace.

Hello Shahana ,
I have crowns on my front two teeth and constantly worry that they may break any day . It has ruined my life . If they break , i don't want to get dental implants as that may spoil my chance of being able to regrow teeth . I will need to look in to partial denture .I read in the posts above that you are in England and doing lot of research on teeth regeneration,do keep us informed . Do you see hope that with in 5 years we may be able to regrow teeth ? Thanx.

Hi Lina ..

According to Dr Paul Sharpe (www.odontis.co.uk) .. with 2-5 years the procedure could be available. One could be hopeful & optimistic. But never absolutely 100% sure. Having said that Surgeon`s has been increasing the bone-density for quite some time. Tooth are also "bones" .. tooth regeneration has been successful in mouse & pigs, these are the two animals biologically similar to human body. When baby tooth falls out from a kids mouth, stem cells has been isolated from that .. those cells was used to grow teeth in the lab. Result was successful. So the function of the mechanics are there. Only thing to figuare out now are the genetical signals to control the size & shape of the teeth.
--------------------------

Your crowns could be fixed with a very good cosmetic dentist. The roots of the front teeth are quite long. The dentist could increase the length of your front teeth but pinching off a little gum. And then redo your crown`s.

Partial dentures are should be second option as you have to take them off at nights; which means the other teeth could shift & move .. & cause problems down the road.

I don`t know the extent of your damage. So I can`t predict what you should do. Consult a few dentist. Don`t just go with your high-street dentist.

Dentists are like "hairdressers" .. some are good & others stinks. Crowns & veneers are part of cosmetic dentistry.
So general dentists usually are not good enough to do those work.

Try to see a reputable cosmetic dentist. For example;
www.londonsmile.co.uk (in UK)
www.advanceddental.com (in USA, my dentist)..

I currently live in CT, USA, since past 3 years. But originally from England. A really bad dentist messed up my front two teeth, so I have veneers on them now. I am sooo angry ..aawwhhh...

By the way, my research for tooth regeneration is out of interest, NOT professional at this stage. I just have medical science background.

Type the keywords; "tooth regeneration" or "regrow tooth baby stem cells" on google.com .. you will find a lot of info.

Shahana , thankyou very much for the information . By the way I live in india .Thanks again.

HI Friends

Here every one has a story to tell about their dental problems. After reading all the
Comments I decided to post one of mine. But first of all I wish Mr.Dr.PAUL SHARPE all the best.

Right from my childhood I had a missing left incisor tooth, which resulted in having gaps in between my teeth. At the age of 15 I had cavities to 7 of my molar teeth and unfortunately I consulted a Young greedy Dentist with out proper knowledge who went on drilling the other 5 of my healthy teeth as a result I have 12 fillings. Now I am aged 23 and once again had refilling which made my mouth a mess. Fortunately I did not loose any of my teeth but definitely I am missing that great smile and hard food. In fact the missing tooth has ruined my life. I don't even laugh when some one cracks a joke. I just can't express in words what's going in my mind. I even thought of ending my self and which is not a solution. I wish let us be optimistic so that some day people like all of us will have a great smile. And I would like to clarify that the ancient medicine like Ayurveda does not have a solution to re grow human teeth. I am not saying these simply with out any proof, in Mahabharatha Karna who had golden crown that he will donate it to a poor Brahmin which it self tells the story. Ayurveda was much popular at that time and not had a solution. So lets hope the modern medicine and technology will provide a solution to have great smiles. Finally I would like to say to all those great minds behind technology that we Humans need Technology that will bring light in the lives of millions who are suffering from various diseases. What's the use of having luxurious technology? Just think....

4 years ago I was convinced (By a radical lunitic doctor) that my colitis was being caused by parasites in my teeth.

I KNOW THIS IS INSANE BUT I WAS DESPERATE AND FELL FOR IT.

I removed 50% of my healthy teeth in hopes that it would cure my colitis. IT DIDN'T DUH!

Needless to say as a 41 year old man I am desperate to have my beautiful teeth back.

Please ad me to your list.

Thank You.

The first DENTIST that is smart enough to offer this service to customers will make a FORTUNE.

I would pay $10,000 thousand for my teeth back.

No problem.

:-)

Now that California has decided to begin stem cell research, will you be doing studies in CA?

I would like to volunteer for any studies. I have one front tooth that was broken in childhood and replaced with crowns, the root is still alive. I also have one side tooth where the root is dead (the doctor did the dry ice test and it just gets cold), but the tooth is held in place by the surrounding teeth and otherwise looks normal. Would both these teeth get to be regrown?

Thank you so much,
Lana

I would be thrilled to be a "guinea pig" for re-growing teeth!

Connie G>

I would like to participate in any trials of this procedure as I have lost teeth

Hi, I am a 30 yr old (20 yr) diabetic. I will be losing my teeth in the next few years due to gum disease and due to smoking (in my early years). I live near london and would love to participate in any studies to help move this process further. Best of luck with the project.

Hey Abhiraj..

Please send me an email to: shahanakamal@aol.com
Nothing is worth killing yourself or taking your life.

I understand your pain .. I was only 17 & highly highly ambitious bright at that time my dentist gave me wrong treatment. I too felt like vanishing for the planet .. i had many dreams but remains unsatisfied.

Where are you?

Look forward to hearing from you

much love

Shahana

Hi,
To dear Paul sharpe and the company Odontis,and to all , I would love to be part of this treatment growing tooth through stem cells as I lost my front 4 teeth and now it is fixed by bridge and cap treatement, plz somebody tell me when will this treatment be available in the clinic, Best of luck to all researchers of this project and I hope for early succsess!

Please let me know when you need someone to participate in this project as I lost my upper teeth and would give the world to have them back.

I think we are a lot of people waiting for something like this. There´s nothing like a new tooth. I´m scared everytime i have to go for dinner with friends. I would die if my tooth falling while i´m having dinner o simply talking with friends. Please, we need this new technique asap.

Hi.

I've been working on tooth regeneration for about 2 years. My body and soul both seem to be benefitting by my working on this project. I'm confident that with a reasonable budget I could grow new teeth in suitable subjects.

The reality is that I have hardly any money, although I'm finally documenting my method, which is happening at www.worldofteeth.com, and in the future I expect to sell my method and my services.

The ORAL HEALTH section of my website details the method I've devised, which is a 5 factor approach to oral health: hygiene, eating, thinking, exercise, and treatment.

There is also a strong emphasis on the philosophy, grounding material for anyone heading towards the high flying technology of stem cells. Reading about the life of a tooth helps to put treatment approaches in their place.

I have specific meditations and theory lessons for tooth regeneration, however, I understand that these meditations may cause problems at other sites in the body (e.g., bone spurs and calcifications) if the user is not healthy.

My meditations are more holistic than tooth germ implantation, yet they are not as powerful either, as I've not yet reached the need to write tooth development meditations.

I expect the gums to harden prior to any tooth sprouting, and if this occurs in my body then I will begin writing tooth development assistance meditations in preparation for teething.

Tooth germs can probably be created in meditation by a skillful application of the meditation processes supported by nutritional support, topical treatment, and so on.

However, my approach is a multifactorial approach combining the various facets of health with specific dietary ad exercise techniques to support cell regeneration and meditation to direct tissue growth.

As such, I encourage anyone wishing to grow new teeth to optimise their general health as a precursor step to growing new teeth as this will improve their chances of a successful outcome.

Since following my method, I've had no need of a dentist, and existing cavities in my teeth are slowly refilling themselves as a result of the practices I follow.

To be honest, this process has taken me very deep inside my life, learning about how I act to cause tooth decay and how to act to cause tooth repair.

Yes, the level of action, not medicine or thought, has been the most powerful for me, especially concepts of self and identity.

Purification of the mind and heart are highly valuable in seeking the complex molecules necessary for tooth regeneration: these organs are powerful organisers.

I wish my material was more organised and edited, but it is what it is. Best wishes to all toothfarmers, personal and professional, including Prof Paul Sharpe, whom I have written to once or twice but am still praying to hear back from.

Sebastian Reed

Sydney Australia

@ shahana,
Why dont you keep your opinions to yourself, instead of touting for punters to go to your website.
A breakthrough has been made and you want to jump onto the pioneers bandwagon, you are no more than a leach shahana !!!!!!!!!.

@ Jaima,

You sound arrogant, illiterate and annoying.

Shahana, on the other hand is in this message board helping people.
If you read carefully she has"no personal website".

You are nothing but a stupid, immature individual JAIMA!!!!!!!!!!!!!

Im a 28 year old male who lost all of his teeth 4 years ago this affected me seriously i jumped from job to job because i couldnt stand the piss taking all of the time i eventually had a nervous breakdown this made me ill for 18 months then once i was better i returned to work and i realised that i have to do something soo i have spent the last year trying to get help from dentists, i went back to the dentist who took out my teeth and he told me that i cannot wear dentures because of my jaw and that there was no hope so i contacted universaty all over the world trying to get help all of them replying sorry we cannot help you at this stage. I then contacted sheffield hallam dental hospital who said we will give you an appointment to come and see us and eventually they didnt so off i went to sheffield thinking this was it finally getting the help i need but this wasnt the case i found out the dentist who took my teeth out didnt really need to do it and if he had contacted the dental hospital before he had done it they would have been able to help but now they will struggle.

so im back to my life with no teeth and no real future, if there is any chance that the regrowth of teeth happens please consider me

Dear Tim,

Your four teeth could be replaced by something called "implants". If your jaw doesn`t have enough bone to support, they could surgically increase "artificial bones".

Contact "Cosmetic dentists". Please do a search on yahoo.com or google.com.
Your best bet is to go to London & there are a lot of cosmetic dentists there.
Here is a link for you.

www.londonsmile.co.uk

http://www.londonsmile.co.uk/html/Services_cosmetic_toothreplacement.htm

Please disregard my previous email regarding implant being a difficult procedure ..
In the USA, they have come a long way, and, implants are not so tough anymore.

Good-luck honey..

Shahana

sorry you miss understood the dentist removed every tooth i had leaving me with none thats why im looking for some sort of help

Tim,

There is a TV program in USA called extreme-makeover .. they transform unattractive people to extremely attractive. That includes your "dental surgeries" too.

One of the most famous Dentist`s info is here. Please contact, write emails & explain your situation. They might be able to help .. they might fly you to USA & give you free treament.

William M. Dorfman, D.D.S.
2080 Century Park East, Suite 1601
Los Angeles, CA 90067
(310) 277-5678
E-mail: williamdorfmandds@yahoo.com
www.loosveltdds.com

Also look at the list in the website below;
http://abc.go.com/primetime/extrememakeover/extremeteam/89924.html

Try to contact all the D.D.S (Dr of Dental Surgeon`s)..

Best wishes

I'm 39 now and I first got gingivitis about 10 years ago. No teeth lost but I'm concerned about the future as I age. Does anybody know of any online support groups for people with teeth problems? Also, has anyone seen the site about using Cell Therapy for Gum Disease? Thanks!

http://www.medicinenet.com/script/main/art.asp?articlekey=47021

Hey Randall!

Love your blog. You first covered this story over a year ago -- how about doing a follow-up?

Cheers,

Andy

Shahana,
I have read all the posts and I thank you for offering support to individuals like myself that have lost or damaged teeth. My story is similiar at 38 I went to a extreme makeover dentist in Beverly Hills for a cleaning and routine examine. I walked out 3 appointments later with 10 upper and 10 lower veneers and 2 root canals on perfectly healthy teeth. This was a negligent, malicious and greedy on the dentist's part. I had no idea what was going on in my head the day I agreed...I trusted this guy and he ruined me. I am currently undergoing restorative procedures to regain my natural smile and to get rid of these CHICKLETS! I have been to 5 experts and they are all appalled at what this guy did to me. Do you know if it possible to regrow tooth structure that was shaved away? i have read a few articles but i can not seem to find enough information. Also, do you know if a tooth will be able to be regrown if a root canal has been performed?

God bless everyone sufferring and I hope all your dreams and wishes come true!

Thom
thomfcat@yahoo.com

Hi Thom...

I am so sorry to hear what has happend to you. You are not alone. Same thing has happend to my front 2-upper teeth. My dentist in England was a very bad, sadistic man.

"Do you know if it possible to regrow tooth structure that was shaved away? i have read a few articles but i can not seem to find enough information. Also, do you know if a tooth will be able to be regrown if a root canal has been performed?"

-- From my readings online I understand that they could regrow teeth even if there are no-teeth left!! However, scientists are still at research stage & nothing is out in the market to regrow teeth!! I just hope it happens within our life-time ..

In America most dentist`s are extremely greedy, commercial. They have learnt a trade & the highest amount of money they could make is by doing "cosmetic dentistry"(veneers,crowns, implants, root-canal etc). So dentist`s here are making suggestions for pretty-much everyone to go through those procedures!! "They don`t want to do what you want them to do .. they want do what they want to do!"

BUT WHY?

Answer: MONEY MONEY MONEY...

Now "Cosmetic Dentistry" means cosmetic or similar to plastic surgery! FOr veneers or crowns preparation - they use this high-speed razor-blades to "CUT" your teeth (what dentists say filing down). First thing they do is cut or narrow each teeth on each-side, they often narrows, shortens, trims to make natural tooth more like a "nail or screw" ...

However, it`s absurd to do that to normal teeth unless an accident happend! It`s a dnagerous procedure! Just if the dentist`s hand moves or fingers slips .. your whole tooth could be destroyed!

Teeth are part of our body, the pain in mouth cause`s all sorts of other illness - such as cardiac arrest or heart disease, lung, kidney infection because of the bacteria in the mouth becomes infected. Additionally, those who has lost teeth knows their smile, their ability to speak clearly becomes difficult. If a tooth is not positioned properly it gives headaches, pain in the jaw & neck.

SOOO please whoever has normal teeth ... please do-not listen to your dentist. Only if you have pain for months or years .. then get opinion. Accept the way you are! The way god has made your smile!

God bless all

Shahana

Hi,
Shahana! I noted that you are so kind to everyone in this discusion.Thats so goood.. I had lost my front 4 teeth 2 yrs back and had treatment of bridge and cap.. but now I feel uncomfortable with that and colour diffrence in teeth.. I want to know that will I be able to have natural teeth by stem cells by removing these fix bridge and cap treatment and one thing more that how these fixed bridged cap teetth can be removed as these are fixed? When will the treatment for growing natural teeth available any hope?..........

Hi Aman...

1) caps or bridges made of "Porcelain" shouldn`t discolor & should last more minimum 10-15 years.

2) Your bridge & cap shouldn`t discolor and your dentist should have matched your teeth color for bridges/caps.

3) Fixed bridge`s/caps could be removed & redone.

4) Every patient is different - whether stem-cell will work for everyone is a BIG Question??

Finally, Aman I wish I knew the answer. Scientists are still at research stage. Please pray & hope that teeth could be regrown naturally.

regards

Shahana

I am also interested in becoming a volunteer for teeth regrowth, I am 43 years old,a single mom of two teenage children.I lost all my teeth in August 2004. I had a set of dentures made and payed alot for something that I aboslutley hate. I live everyday feeling extremely sad and cry all the time, I feel like a freak. I can not stand the abnormal feeling of not haveing teeth and the feeling of this horrible denture. This would be a dream come true. I look at myself in the mirror and can't help but cry, this took my self-esteem and self-worth with it. I pray to be able to smile again and feel happy, I want teeth that will stay in my head and not in a cup or my pocket. I have been wanting dental implants but can not afford them. I found this website and could not believe it, I was thinking to myself why can't we regrow more teeth, sharks do..I think. Please, I would be grateful to be involved with this project it would ba my dream come true!

I am also interested in becoming a volunteer for teeth regrowth, I am 43 years old,a single mom of two teenage children.I lost all my teeth in August 2004. I had a set of dentures made and payed alot for something that I aboslutley hate. I live everyday feeling extremely sad and cry all the time, I feel like a freak. I can not stand the abnormal feeling of not haveing teeth and the feeling of this horrible denture. This would be a dream come true. I look at myself in the mirror and can't help but cry, this took my self-esteem and self-worth with it. I pray to be able to smile again and feel happy, I want teeth that will stay in my head and not in a cup or my pocket. I have been wanting dental implants but can not afford them. I found this website and could not believe it, I was thinking to myself why can't we regrow more teeth, sharks do..I think. Please, I would be grateful to be involved with this project it would ba my dream come true!

I hope this is available soon, and it is affordable! I hate having fillings, etc. I wonder if it will be available in Canada, and how long Health-Canada (government health agency) would take to approve it if it does come around?

Those in England are lucky that their healthcare covers dental treatment, here we must pay from our pocket, although we can deduct health costs on our income tax return! (Doctors visits, hospital, etc are covered but not dentists)

I heard that it could still be another 10 years before it is available to the public in general. I wonder how much it will cost, and it the research will pan out!

Shahana, First I would like to thank you for all your hard work in responding to everyone and doing the necessary research. I am interested in this subject because I have chipped a front uper tooth 5 years ago and it has been filled 3 times since. I am afraid there will be nothing left of my tooth after so many fillings because they need to take some of it off every time they refill it. I am wondering if you have heard or read about solutions for chipped tooth? Suppose this research becames sucess for people who are missing teeth. What can be done for those with chipped tooth then?

And I will add that I do believe regrowing teeth will became sucessful some day. It will be a reality some day.

Thanks,

Shuun

Dear Shuun...

Chipped Tooth .. hmm ... best solution is to put "veneers or crown".

Good fillings should stay for 10-15 years. If you had to refill 3 times that means your dentist is not doing the right treatment for you.

I suggest you to get porcelain veneers.

For all my readings I understand .. they will be able to regrow a whole tooth once this procedure becomes available. Which means, there will be a complete 'new tooth' growing to replace your chipped tooth.

I also am praying hard that this procedure becomes a reality. They are able to clone a human, why not a tooth? Right. Also people who has problems with eye-sights are now correcting their vision with 'lasik'(laser treatment) .. God willing teeth could be corrected too.

Best wishes

Shahana

We all pray that it will be available very soon, and that this will be affordable (not just for the rich and famous)
I bet everyone would love to replace teeth that have fillings (bad for the health - although they say it is not!)
This would be great even for people with crowns!

Too bad governments are not investing in this research, as well as a vaccine for cavities! I heard that they have sealants that they can use on teeth now to help (not stop) reduce the chance of cavities. It is a thin plastic layer on the teeth, it would need to be replaced every so often, no harm to the teeth!

I hope the growth does involve growing a fetus at any stage (as that would cause an ethical delima)!!

Hi. I would be happy and very happy to be a part of any trial that there is to grow teeth. I would travel or do whatever is necessary to have this take place. Has anyone found a dentist or trial on this. I would be the first to volunteer.

Let's see what's going on now as London just had a terrorist attack (where a lot of the research is going on!) I hope this is not a setback!

As for volunteers I heard that they have over 1,000 people ready!

I hope the volunteers they have are a representative sample based on ethnic background, as well as male/female.

I don't know if it will be available on the market within 5 years, as it would take time to train dentists, as well as setup labs to grow the cultures! And yup government regulation and red tape can take years to over come. The cavety vaccine is in its final stage and hopefully should be ready for all. I heard that it would be less than USD$200 but it would be worth it! I'm sure insurance companies would pay for the vaccine as based on the time/value of money they would have to pay out less in the long run due to cavaties. This is a win/win for insurance companies and all of us!!

Thanx Shahana for ur reply... I heard that this treatment wiill be available by 2007. Is it true? I wish this treament would available soon. You are right that scientist can clone whole human then why not teeth! All those researcher on this tooth regrowing should think this also.. Ok guys lets hope and pray for early sucscess and availability of this treatment..

Aman,

It does not say will be ready by 2007, but they hope to have clinical trials by then.
Do realize that they don't even have the cavaety vaccine out yet. You would want this if you are going to spend money on a new tooth eh?

To add your prayer, ensure that it is affordable, and will the insurance cover it??

I'm not sure if they can really do this. I haven't seen any news releases doing a google search for anything new for 2005. Anyone have any info?

It seems like everyone is keeping very quite, either they are very close, or they are way off! If it is available soon, hopefully it won't be expensive. They can capitalize on economies of scale rather than charging more, thereby everyone wins!

Details anyone?

I haven't seen any press releases regarding this as well. There seem to be several different timelines regarding trials and/or rollout of a product. In a 2004 article, Prof. Sharpe says possibly 2 yrs for clinical trials, a Japanese article talks about shipping a product that is "tooth germ" by 2007. I do not know what that is exactly. Several older articles that are dated Dec of 2000 say 10 -15 yrs, but I believe stem cell research is progressing faster then they anticipated 5 years ago. If anyone has current information, please share it with this site so we can keep each other informed.

Thank you,
Thom

This is the only link I found that seems to be from 2005

http://www.findarticles.com/p/articles/mi_qn4153/is_20050525/ai_n14642374

It seems several groups are researching not just Sharpe, but American, Japaneese, and Luxumberg groups!

http://www.stemnews.com/archives/000475.html

http://www.channelnewsasia.com/stories/afp_world/view/83069/1/.html

The above articles might be of interest....

I read some articles saying that it's 5 years away, others say 10, and others say 20 years any clues?
It depends on who is doing the research, etc. and these are from articles in the same year!!!

I have been researching articles by:

Prof. Sharpe(Odontis)
http://www.cnn.com/2004/WORLD/europe/05/03/teeth.replace/
http://www.odontis.co.uk/
http://www.medicaltalk.org/Grow-your-own_to_replace_false_teeth-476054-10-a.html

Pamela Yelick, Ph.D
http://www.freemanlab.org/people/yelick.htm
http://www.abc.net.au/am/stories/s745807.htm
http://www.news.harvard.edu/gazette/2002/11.07/11-teeth.html

Mary MacDougall, Ph.D
http://peddentdx.uthscsa.edu/macdougall.html
http://www.21stcenturydental.com/smith/education/human_teeth.htm

Dr. Tony Smith
http://www.stemnews.com/archives/000475.html

Pamela Gehron Robey, Ph.D and Lawrence Tabak Ph.d
http://www.stemnews.com/archives/000361.html

Dentigenix
http://www.dentigenix.com/Press_Release.html

Forsyth Research Institute(Harvard University and working with University in Brazil)
http://www.news.harvard.edu/gazette/2004/07.22/23-smile.html

Hitachi Medical Corp.(working with 5 Universities in Japan)
http://www.atimes.com/atimes/Japan/EF06Dh02.html
http://www.cleverdot.com/~hwny232/news822.1.html (scroll down to the 5th article)

I think not much is being said, is because these companies are thinking about the commercial value of their technology. So, maybe they are keeping a tight lid on their discoveries to protect their investment. For instance, Hitachi Medical Corp. has 5 universities working on different components of this process to regenerate teeth and they are talking about projected revenue with the launch of their product in 2007. Prof. Paul Sharpe has set-up Odontis and Dentigenix is licensing technology from Forsyth Research Institute to further their project. Currently, $895 million dollars a year are being spent on dental implants. These companies want a piece of that action and that type of competition gets us closer to having our natural teeth back.

Also, US companies and/or universities are partnering with foreign companies/universities, is this because research in foreign countries have less restrictions then the US?

I hope these articles help and if you come across a new article please post it.

Also,

I'm suprised that people are not also taking about a carries vaccine? Prevent them in the first place! I read somewhere that it is in clinical trials any news?

I hope that it is only a few years away, and that it is affordable! I came across this site as I need to get a crown for a tooth as part of it broke/chipped off on a tooth where i had a filling!

Let pray that it will be ready only a few years away.

From reading some of the articles I read they will be able do this without resorting to creating a human embro, so it won't cause an ethical (and even a reglious) delima. I hope this is true otherwise I will never be able to get rid of that crown! Any info on this part of it??

Thom,

I hope you are right that these companies doing research will result in treatment for all of us soon (replace damaged teeth, teeth that have fillings, teeth with crowns etc).

I just hope it will be available to the general public within the next few years!

I did not find any other discussion boards talking about this when I did a google search. This must be a hot topic!!

Hi

I am very interested in this research and was wondering when it will be widely available as I want to be a guinea pig!

I am 41 and in the later stages or peridonitis and I am expecting to start losing my teeth. I hate the thought of false teeth.

Please reply asap

Thanks

Joan, London

Apparently, there are trials taking place in human .. read the article below..

http://www.chronicle-future.co.uk/subject/person16.htm

Shahana,

I hate to say this but that is a prediction on the future and not a real article. Look at other articles on the site and you will see what I mean. I hope you are able to find news from a more reliable source!

The article talks about injecting some chemical, we know from the on-going research that this will be steam cells not the chemical noted!

Hi Fred!

A quote from the article;

"In Seed's case, his gum was injected with a protein called BMP-4, which inhibits the gene that makes teeth develop as molars."

My first degree was Biomedical Science & one of my best friend has done her PhD in Gene Therapy/Gene mapping .. So my knowledge is ..

Stem cells research is all about'genes. In another words gene-mapping is stem cells research.
Plus, genes are mostly made of 'protein composition' when you get down to moelcular-structure or chemistry behind it.

Protein(BMP-4) is probably extracted from stem cells, unless of course it is 'lab-created'.

I hope it helps you to understand a little more ...

By the way, all the articles are simply "predictions" so far. However, a lot of research is underway, let`s keep our fingers-crossed!!

God bless everyone..

Shahana

When i did a google search this was the only blog (board) that i found active on this topic!

I hope this research is sucessful, affordable, and available in the next few years! As well as other research related to dental such as study of self filling caveties, a cavety vaccine etc.

It's amazing that they can regrow this without resorting to creating a human embro so I wonder why people are so against it? I was doing a google search on organ donation (when you are gone that is), and many authorative on various ethics say that it is okay if it improves the life of another person (which it would)!

I don't see why some would consider this type of research unethical as it does not involve creating an embro??

Hey this is a 2005 Article!!!!!

June 10, 2005
http://www.sciencedaily.com/upi/index.php?feed=Science&article=UPI-1-20050609-19144700-bc-us-stemcellbank.xml

NIH (United States of America National Institute for Health)
Wants to promote banking of baby teeth and wisdom teeth for future stem cell research

This would be so awsome. I as many other would love to be in your test group. As my situation is the same in gerneral as wanting to have there teeth regrown. How ever differs so much from most people as to the reasons they are gone. I am a disabled 48 year old women who for the first time in her life has taken an interest in doing things for myself. this would be one thing I would love to have my beautiful smile back as well as to eat some of the foods I have missed. If you would like the more information please contact me keep up the good work hope to see you all soon. Thank you, Rhonda.

Paul Sharpe is giving a lecture
http://www.oxdent.ac.uk/cgi-bin/enrolments_bs/appstar/D=calendar/V=day/YEAR=2005/MONTH=Sep/DAY=8

Oxford University Sept 8, 2005. Anyone attending these lectures please share exec summaries!

unfortunately, the dental industry have bought off the research teams and these will release the results only in 10-20 years from now. we people must raise a protest against dental corporations taking over the research companies and delayng clinical trials in order to maintain their present increasing profits and the enormous numbers of dental practitioners.
MINA.

Rya,

Where did you come by this information? Several companies (Dentigenix, Odontis, Hitachi Medical Corp., etc.)have been set up to benefit from this new procedure and it would mean billions of dollars to the dental industry. I don't beleive all these corporations think this new technology will stop people from buying their products or will this mean the end of any/all dental procedures. But, this will be an additional service available for probably more money then other treatments.

Also, large investments have been made by corporations, universities and private parties, to make this a reality in the very near future. I have researched this technology and I feel it is moving faster then anticipated because these companies are forecasting sales within the next 2-7 years.

I do not doubt what you are saying and there is probably nothing we can do, except support the companies not involved. I will go to another country like Japan, U.K, South Korea, Brazil, China, Sweden or Norway to name a few currently working on this procedure.
Can you please name the companies involved? Thank you.

Is there any news on growing tissue that could be added to teeth(replace missing/worn enamel)?

elementary Thom, elementary. no need to go into names . implantology started some more than thirty years ago and only during the last ten years has it become a welcomed option. this happened after the dental industry felt confident enough of the prospective huge profits involved in it for her.
Teeth regrowth has the potential of erasing the dental industry and placing big demands on the dental profession. so it stands to reason that it's going to be science fiction for many, many years unless people do something about it.
RYA

I am interested in volunteering please contact me at 847-980-8644.

Rya,

Technology changes and has exploded in the past few years, actually implants have greatly improved in the past few years due to R&D. Some of the research found in the dental industry is being used in other areas of health. As an example some of the finding of the stem cell research are being used to treat various illnesses ie. ALS, MS etc!

When you talk about dental companies do you mean Crest, Colgate etc. I would think they would love this as it would increase the market for their products ie. toothpaste, toothbrush, mouthwash, floss etc.

Fred, I mean those companies based on fabrication of dentures, bridges, crowns, implants and all the materials that go with it( acrilic, titanium, cobalt, ceramics etc...).
Regrowth of teeth is going to replace all this, and the parties involved are going to do all they can and more, so that regrowth of teeth stays science fiction for many, many years, unless people will be on the alert about it and try to prevent deliberate delay in research and clinical trials.
RYA

Rya,

You say its elementary and no need to name names but that doesn't make any sense. How can we be on alert for these deliberate delays if we don't know who you are talking about. Again, who are you referring to? Just give me a name so I can research it.
You said, "Teeth regrowth has the potential of erasing the dental industry and placing big demands on the dental profession".... I think it would be a longtime before this new technology will erase the big companies that make implants materials. Usually, corporations in the technology and research game know they have to keep up with the latest advancements or they will not survive. They tend to invest in companies and/or develop their own technology, so they can profit as well. What about those giant corporations like Crest, Johnson & Johnson, etc. that have alot to gain when the millions of people start taking better care of their NEW natural teeth. You are right about it placing a large demand on the dental professionals...they are going to be so busy they won't have time to count how much money they are making.
There are millions of people around the world that have lost teeth that don't have implants. I know these people will do whatever it takes to have a natural tooth vs. a fake one.

Also, other countries and corporations outside the US are developing this technology and they know whoever develops it first wins! BILLIONS $$$...thats a big incentive and I will go to that country if need be.

Fred, I totally agree with what you are saying about the dental research helping other diseases. I read an article that discussed regeneration of organs and they are supporting regenerative dentistry because if a tooth doesn't take, it's a matter of extraction vs. an organ that requires major surgery and failure could lead to death.

My dental hygenist said that this would be a boom for them (hygenists) as people would want to take extra good care of their new teeth. From she has heard a lot is being spet on research!

Also said sometimes they get people in the dental office who grow a third set of teeth, Wow. I wonder why we don't get more teeth, I wonder how these people are able to get a third set of teeth?

I wonder how much Canada is spending on this research? I know that the United Kingdom, Japan are spending on this any other countries?

As I understand some tests were done on animals (not us humans - at least from what I know) and I was wondering what is the quality of the new tooth? Is it of an equal or greater quality than the new tooth? Just think if tooth regeneration works what impact it would have for general human health - treatments could be found for other illnesses! God willing treatments will be found for these as well.

I know this is not science fiction, but I really wonder if this will be available for us during our life time, as we don't even have a vaccine on the market for dental bateria etc. (Any info on this? I know this is a regrow blog, but this is a related topic).

Julie,
I think the quality and looks of the new tooth can be manipulated and as far as I know, tests done on animals (mice, pigs) were successful. As far as us humans are concerned, I am not optimistic about it being available in the near future, not because it's not possible but because it stands in the way of powerful factors.I wish I were wrong about this. Anyway, people living close to the scene of research such as London, San Antonio in Texas, and other places should "keep an eye" on what's going on and report to the world.

Rya,

It's good to see that the research as proven the quality of the teeth can be the same or better!

You say powerful factor such as companies that make dentures etc. Did you know that IBM's main line of business at one time was typewriters? They had to adopt and change in order to remain competitive. Companies like Olivetti etc went under, as they did not keep up with the changes in the market.

I'm sure that the companies you talk about will change otherwise they will not survive!

Could you name some of these companies that are these powerful forces? If it were elementry we would know who they are by now.

Also at one time IBM said the world wide demand for computers would be 5 (five).
Microsoft said at one time 640K is all anyone ought to need!

Both were proven wrong! All companies must adapt and change!

Investors are interested in future earnings of the company. If they produce the same old stuff it shows they are not in growth, and investors will not invest. On the otherhand if they invest in R&D, and put these to action they can increase revenues and thus shareholder wealth. Investors care more about how the firm will do in the future rather than how it has performed in the past!

My question to you is why these 'elementry companies' wouldn't want to increase shareholder value.

That's exactly it. Companies must change and adapt, but that takes time, a lot of time, many years. Until then big efforts will be made to delay the new invention from being put into practice. It's no simple matter. If one could regrow teeth , hundreds of technicians fabricating dentures and bridges will become jobless.So will those dealing with supplies of materials for the dentistry services.

But thousands of bioscience professionals will gain employment. I think these technicians will have to re-educate themselfs. In any field people must upgrade their skills this includes techicians, what if you didn't upgrade your skills wouldn't you be out of a job in a few years? Only hundreds of technicians? I think when Ford has their shut-down they lay off far more people. A few hundred people can easily be retrained!

I think companies will re-train their staff to deal with these changes so I don't think these people will be "jobless"

It does not take companies a lot of time to change and adapt. I think companies such as Crest, Johnson & Johnson are larger players then the denture companies! As well as noted by Thom even other researchers are behind this as regrowing a tooth although complex is not as hard as regrowing a kidney etc. So I think there is a lot of backing behind this not only from the dental profession, but from other areas of medicine!

rya, you still have not answered my question!!
Could you please name some of these "elementry companies" by name

Ref: "elementary comapanies" to delay tooth regeneration!!??

Hi Guys!

There are NOOOOOOOOO elementary companies to stop R & D. Instead there are surge for increase in research, so other bio-tech companies could take advantage! And, scientist`s working in the field wants the treatment available asap ..

Companies listed by 'Thom'(Dentigenix, Odontis, Hitachi Medical Corp., etc.) are established/formed by investors from private & public sectors. Imagine this new companies means more jobs for scientists & technicians.

I think "rya" made a aloof or dogmatic (without proof) comment .. that`s maybe because, she doesn`t have much knowledge about the area.

R&D will continue to benefit the lives of millions. Having said that crowns, bridges & veneers will not be vanished so soon. Tooth regeration may-not work for everyone...

Shahana

These are articles that are related to this year!

http://www.stemcellnews.com/articles/stem-cells-today-show.htm - June 8, 2005
http://www.stemcellnews.com/articles/stem-cells-teeth.htm ----- May 25, 2005
http://www.stemcellnews.com/articles/stem_cells_growing_teeth.htm - March 9, 2005
http://www.stemcellnews.com/articles/stem_cells_teeth.htm - Feb 20, 2005

Looks like from one of the articles Prof. Sharpe will be conducting trials within the year!

HI
PLease think of me as one of your test patients ,i have lost a lot of my teeth and have to wear a plate I have hidden it from people because it feels awful,and it would be great to eat properly again, it realy does affect my state of mind.Can you let me know where i could apply to be a test case. nmclear@hoo.com
thanking you
Nanette

Julie and Shahana,

Thank you for supporting me in the "Elementary Discussion." We still have no names from Rya, thank goodness for that. I was little upset after reading her opinions and I doubt there is much credibilty to her claims.

I truly believe this technology will be available soon to us all and I look forward to discussing new findings with you.

Thank you again.

Nanette,

Please note that we are not doctors nor are we actually involved in the actual clinical trials. We are just like you we would like to know more information about this exciting break through. Read the previous threads, and share your comments etc.

Let us put aside differences of opinion and waste no more words on that. Let's only hope and pray that the new and exciting technology will indeed be available soon and that we will all benefit from it. Let's concentrate on the news coming from the research field, if there are any such news.

rya...

Honey you have not done enough research or even read the previous threads. I also don`t feel you understand medical research. These companies mentioned by 'Thom & myself' .. are NO JOKE!

They formed companies to find revolutionary success. The primary test`s were successful on rats & pigs. "Every medicine/drug & treatement that are available in the market to save our life is FIRST tested on rats & pigs" ... The reason is human-body functions matches closest to rats & pigs.

So now that the scientist`s were able to grow NEW teeth by stem cells in rats & pigs.. that means probability of being successful in human is very high.

But, I think the time has come for god to listen to all our prayers too.

Shahana

I would like to re-grow my new tooth. Where is this treatment available?

Shahana,

This article says that Prof. Sharpe will start clinical trials within a year!!
http://www.stemcellnews.com/articles/stem-cells-teeth.htm ----- May 25, 2005

Any updated information on this?

Shahana,

Alot of people are asking about signing up for human trials. I haven't been able to find any information...have you?

At the bottom of the Odontis homepage (www.odontis.co.uk) it says this: "The Odontis technology is still in the development stage and it will be some years before it will be ready for clinical use. Please note that we are not seeking volunteers for human trials and cannot enter into any correspondence regarding when or where the treatment may eventually become available."

Thank you.

Thom,

I called up Dr. Sharpe once last year regarding clinical trials on human. He told me he has more than 1000 voluteer`s already .. So his plate is full.

You could email him or the department .. ask if they are starting clinical trials pretty soon. This is the only way.

I wish I could help you guys more. But, I too am desparate for this treatment .. if it becomes available. Wrong treatment on only two of my upper teeth made my life completely miserable.

"Amina" .. thanks for the info. Let`s keep our fingers crossed.

love

Shahana

Shahana, as you seem to have had contact with Dr. Sharpe maybe you could find out if these clinical trials have started. Can anyone confirm the article that Amina was kind enough to provide with another source (if this is true it may only be a few more years!!)

Also I heard talk about a cavity vaccine, ginavitis vaccine etc. (If this works, down the road the only need for tooth replacement would be due to an accident, or just that you didn't grow a set of teeth). Just think no one would ever be scared to walk into a dental office again. As well such a vaccine would be useful for those who can't afford dental care (not all health plans, or national healthcare plans cover dental care) - as this would keep costs low in the long run. I think the insurance companies would pay for a vaccine as it would reduce the number of claims they have.

Interesting article on Stem Cell Research!

http://www.stemcellnews.com/articles/stem-cells-catholic-grant-adult-cells.htm

The Catholic Church "Australian" is supporting stem cell research on adult stem cells, according to the article they are contributing EUR 60,000.

So I think the "elementry forces" don't really exist at any level. I don't think the other major faiths have anything against adult stem cell research.

Hi Julie...

I have emailed Dr. Sharpe following your request. Let`s hope they will respond.

Shahana

Hi. My name is Dawn and Shahana I want to know who to talk to to be a part of any trial I can get in on. Who can I talk to or email? Last year I had an "accident". I was raped and beaten and my Dr's said I would never wake up from the coma that I was in but I did at the begining of this year. Well I woke up and 5 of my front teeth are missing. I want them back. Not implants the real thing. Who can I contact to be a part of this? Please help. My telephone is 817-795-8269. Thanks.

Dawn

Shahana,

I have contacted several of the research development companies and it seems as you've said, they have quite a few test subjects already in place. So, I contacted several third party agencies that will place me with the appropiate treatment facility. I have not paid any fees and I am awaiting responses. These agencies claim to have contacts with research development companies in several countries around the world that specialize in gene therapy, stem cell therapy, fertility and regenerative tissue treatments.

As soon as I get more info, I will pass it on.

Thank you.
Thom

If this works and becomes widely available it will be a step forward for all other types of research. I know of people who are following other (other than dental) stem cell reserach hoping for a cure. From the articles I've read dental stem cells may lead the way for other stem cell research!

Dawn..

I am soo sorry to hear about your situation.

Unfortunately, the 'real-thing' is still at research stage. It is not available for public in the mareket. It may take 5-10 years before any concrete-result.

Sorry, honey. Consult a few dentist. Implants might be only way for you now.

Shahana

Shahana,

when you say 5-10 years before any concrete results I assuem you mean testing! So this could mean it would take 20 years before it's available to the general public!

Dawn sorry about your situation!

Dear Julie ..

According to studies & articles .. they are predicting possible treatment within the next 5-10 years.

But, first thing is "success rate on human" .. scientists needs to see the test`s results on human .. then the whole process of new treament/medicine or drug is a very lengthy one. It takes years.

But, Japan`s are working on tooth-regeneration too! Japanese are always few steps ahead & hush hush. They don`t give much info to public until the product is ready.

I wish this treatment would be available tommorrow .. but, my tommorrow never comes!

love

Shahana

Julie and Dawn,

I have been researching these treatments extensively and making contacts in the industry regarding treatments. In my opinion, I believe human trials will start within the next 2-5 years. They have had successful animal testing in 3 mammals, which means humans could be next. Several of the articles are already a few years old and stem cell research is advancing faster then expected.

I contacted a company that handles placing individuals looking for organ donors, stem cell therapy, and other alternative medicines. They responded to me with rather quickly and I've attached their email for you to read.

Dear Thom,

Thank you for your inquiry. We are contracted by six major research institutions throughout the world. Two in South East Asia one in South Africa, One in Australia the other two are in Europe! Germany and England.plus we are in contact with many Universities throughout the world. I have looked at our records to see who is dealing with Tooth regeneration we have two institutions that are currently dealing with teeth regeneration. One is more advanced than the other. I have contacted this institution to see what there requirements are regarding your request,

They would like to know which teeth you are looking at replacing plus your age! I gather from your email that you are looking at a full natural regrowth of your teeth.vis stem cell techonogly. This institution has had successful trials using mice. but they still think it will some 12 to 18 months before they have the right formula for human regeneration projects.As you would understand there is a lot of research still to be undertaken to get the end result that everyone requires. Some of the requirements are;

* To understand cell-protein, cell - protein and protein - crystal interactions associated with the creation of hydroxyapatite composite tissues.
* Understand the cell to cell interactions and cell - to - extracellular matrix interactions required for dental tissue formation and biomineralization;
* Understand how interfaces between one mineralized tissue and another (form enamel to dentine to cementum to bone) are formed and how biology mediates their association and the dynamic. but firm anchorage of teeth to the jaw;
* Acquire an understanding of how mineral formation is initiated and shaped to achieve the esthetic, mechanical and scale properties of the original tissue.
* Understand and ultimately control the organization of extracellular matrix by cell surface nano - mechanisms.
* Develop stem cell technologies for tooth and supporting connective tissue regeneration.
* Finally, Be able to recreate functional teeth using biological principles.

Recent experimental advances made in post - natal stem cell research, including isolation and characterization of stem cell derived from human dental pulp, craniofacial bone and other orofacial tissues.Will provide the basis upon which the stem cell technologies needed for human teeth reconstruction and regeneration.

Thom you can see that there is quite a lot of development and research still to do. As for fee's we are not able to set a fee at this time. We will need the number of teeth required, as well as what type of teeth you wish to replace. This institution has indicated that once they feel confident that they have the technology required they will than start a limited human trial with about 12 subjects they have been accepting a limited number of clients for the proposed trial that they hope to start in about 18 months time I believe that this institution is several years ahead of any other institution in the world as far as teeth and cell regeneration work goes. Should you be interested in further developments from this institution or should you wish to add your name to their project list than please contact me for details. Once I have your requirements regarding number and type of teeth required than I should be able to work out a fee structure for you.Thank you again for your inquiry and I hope that this has been of some help to you.

Thom to be listed in our data base we charge a fee of $150.00 U.S. This is a once off fee. Thom for details on how to make payments to us please contact our public relations department. Thank you.

I replied yesterday with the teeth I want replaced and I will forward their response.

Thank you.
Thom

Hi Thom,

Look at this article

http://www.nidcr.nih.gov/Funding/CurrentFundingOpportunities/RecentlyCleared/BuildingATooth.htm

It seems like parts of your letter are from this site. I think .gov refers to american government sites.

Fred,

Parts of the letter..lol. I think the whole letter came from that site. Just goes to show you, besides the dentist that took advantage of me there are individuals and companies out there as well. Read the letter they sent:

Hi Thom,

Thom thank you for your reply. First off I do not think scammed is the right word to describe your case! Conned would be a better word I think! Its the greed factor, It is everywhere these days I'm afraid.

You most certainly had some unnecessary work preformed on your teeth from the sounds of it.Now we are left with quite a lot of work to correct the problem.Thom I have spoken to one of our directors who has contacted our friends at the Asian research institution to see what their views are on the subject and what the overall cost to you would be.

First off they think they can help you get things back in order. As for the fee's this is a bit of a tricky question as I'm sure you will understand with the cost of research being so high I believe that they have spent some 5 Million dollars to date on teeth research alone, they as with most research institutions are all looking at re coving their outgoing costs as soon as possible. Dr Wilson one of our directors has pointed out to them that the cost must be kept to a reasonable level as to be affordable by the average person..

In your case as there is a lot of work to be done he asked them for a commitment as to cost for your case alone as they said they do not know what problems they will encounter along the way, but they have informed us that a fee of $40,000.00 U.S. Would be acceptable. In view of the work required we feel that this is a fair costing of the procedures required. They have also indicated as the first couple of trials will be on a restricted basis with only a limited number of clients will be accepted into the first two trials they think no more the 30 people in total will be accepted and it will be a first come first served basis. We can accept that.

However as Dr Wilson pointed out our clients who we refer will expect results on the positive side and we as a referral center want some guarantee that the procedure will reach a satisfactory con collusion for all involved. He has proposed that Genetic Solutions collect a 50% deposit at time of client registration, And that Genetic Solutions will hold the fee's and we will pay the research institution at the time that the procedure is carried out at that time the client will also have to pay the remaining 50%. If by chance the procedure dose not take place than the deposit will be refunded in full to the client. They have agreed to these terms which I think is a fair deal for all involved as you are protected we also protect our trading name and the institution will have a guarantee from us that they will receive the fee's in due course. They have told us that they are holding the names of nine clients who have already joined their waiting list so that will leave us with 21 places to be filled if there cut off point is 30 clients. Should they decide to reduce the number accept for the trials we will have no control over that side of things that is their choice. However we have requested that all clients be accept on a full confidential bases with no release of client details to anyone at all without written consent of you the client. This they have agreed to.

Thom if you feel that we can be of service to you than please contact me for further details. And please remember you are under no obligation to take up this offer. I trust that this has been of some assistance to you. And please feel free to pass on our details to your support group. Thank you should you require further assistance than please contact me.

There is no way in HELL! I would send $20,000 as a deposit to these guys. As desperate as I am, I will not be conned again. Maybe this company is legit who knows, but I am not going to risk it. I have been told that it would be very difficult to get my deposit back (next to impossible) from a foreign entity.

Fred, thanks again for finding that letter drafted by NIH.

Regards,
Thom

Thom,

The reason I caught it was as I am doing a correspondance course part of the module requires on line discussion. Sometimes if something looks too good, just do a google search on part of the text and Bingo!

I just hope that the legit research that is going on will prove some results. I don't think you should have to pay money to be part of a clinical trial. It goes to show you what type of people are out there. I think that the legit companies that are doing the research can direct you the companies that are handling the test patients if they are still excepting them. Shahana noted that Dr. Sharpe has over 1,000 people on his volunteer list (which I assume is a representative sample, given that London is now a multi-cultural city)

I think the legit trials will not just accept you like that, they will want to see and evaluate (again no money). The reason is the money will be made that the time they can market their services on the open market. By pre-evaluating you they can have a representative sample of people that is considering gender, cultural background, nationality.

I am praying as well that something will be available soon (in the next few years). We just have to be sure that we don't get tricked by such people!

I was just wondering how did you find these clinical trial sites?

By the way the US$20,000 would be $24,344 for me taking into account current exchange rates that is a lot of money!!!

Thom...

Please DO-NOT take part in this scam! You see in a clinical trials you will be a "ginea-pig" or a "test-sample".
Many legitamate institutions will pay you for taking part in their experiment for your time & the risk involved with it.

As "Fred" pointed out above. Clinical trials are usually done on a large sample .. more than "thousand" human trials.

Whoever, has responded to your search is trying to ripe you off! Not only that, the language of the emails are very poor & unprofessional. By that you should know it`s illegitimate or bogus!!

Thanks for sharing your experience with us though.

Also comments on this discussion Posted by: Sebastian Reed on March 29, 2005 09:28 PM .. Note that guy also has some-website & he is playing with weakness of mind. He is asking for donations from people all the time. You could do a google search on this guy!

Shahana_

Fred and Shahana,

The company is called Genetic Solutions (www.geneticsolutions.org) check them out. I sent another email that I am very interested and ready to sign up...I just want to get an address on this joker. Once, I have all the info on this guy I will post it as a warning to others.

Thanks for looking out for me.

Thom

Thom,

I wouldn't be surprised if they are located in some country that does not have strong legal rules. If you want to be part of a clinical trial your best bet is to contact the companies doing the research, and pray that that they answer you and pick you for your research.

I am sure that they have a lot of people already. I am sure when the clinical trials hit the street we will hear about it!

I just did a whois search on the domain this is what I got

Registrant Name:William Ashford
Registrant Organization:Genetic Solutions
Registrant Street1:111 Lords Place
Registrant City:Orange
Registrant State/Province:NA
Registrant Postal Code:2800
Registrant Country:AU
Registrant Phone:+61.263604886
Registrant Email:geneticsolutions@itxpress.com.au
Admin Name:William Ashford
Admin Organization:Genetic Solutions
Admin Street1:111 Lords Place
Admin City:Orange
Admin State/Province:NA
Admin Postal Code:2800
Admin Country:AU
Admin Phone:+61.263604886
Admin Email:geneticsolutions@itxpress.com.au
Tech Name:Domain Administrator
Tech Organization:HyperMart
Tech Street1:70 Blanchard Road
Tech City:Burlington
Tech State/Province:MA
Tech Postal Code:01803
Tech Country:US
Tech Phone:+1.8772875929
Tech FAX:+1.7819988586
Tech Email:domreg@hypermart.net

Fred,

This guy is crazy! I emailed him pretending my attorney wants to draft an agreement and place the money in an escrow account with established terms and conditions. He said, "NO, that is not how they do it." He went on to explain that they invest the money in low risk investments to collect their fees. I contacted a broker and $20,000 in a low risk account might yield conservatively $500- $700 over 2 years. So, I contacted this guy(James Denning-if thats his real name?) and said, I will pay the interest in advance but I still have to put the deposit in an escrow account. I went on to explain that this gaurantees their fee upfront and I am protected by the escrow account, if delivery of said treatment doesn't happen. I can't wait to see his response. You are absolutely right about sending 20K to Australia is like flushing it down the toliet...I would never see that money again. Shahana commented on his grammar, he is obviously cutting and pasting phrases from articles on the web. My insurance settlement will be saved until I find a reputable organization. I'm finding this rather amusing and educational because it has me on the lookout for these scam artists and there tricks.

Thanks,
Thom

A reputatable firm should have no problem with Escrows. Escrows are commonly used in business for various transactions. Although Australia is an industrailized country, a scam is a scam!

If you really want to take if further Call Willam Ashford at the number listed above. They will really wonder how you got the phone number! Just tell him that you will be "down under" in the next few months and you would like to see them.

Hi,
I was reading your posts any new information on tooth regrowth? Any theories on when it will be a reality?

the human trials have already started..please google Dr. Rene d'souza name at the univ texas houston..this yr in june they extracted molar teeth of 20 patients and tried growing the roots in culture media..some tooth development was noted..i believe scientists will actively start human trials within a year..GL

I have been communicating with Dr. Sharpe's office for sometime. They sent me an email I thought I should share with everyone. If you can donate $10, $100, etc., it would really help.

Dear Mr Fleming

Your correspondence with my colleagues at Odontis and Kings College
London has been forwarded to me so that I can communicate with you
directly.

All the research on producing human biological replacement teeth is
carried out in my university laboratory. The translation and commercial
aspects are supported by the spin-out company Odontis. I understand
that at present private "investment" in Odontis is complicated. However
I wanted to alert you to a new initiative that is about to be launched
in my university research. I have secured money from the university to
refurbish new laboratories to create the worlds first, Centre for
Regenerative Dentistry". The Centre will be purpose built to house my
research in addition to several new scientists I aim to recruit. The
direction of the Centre will be to pursue cutting-edge research in
dental regeneration.
If you are interested in making a donation to support the running of
the Centre and/or provision of the some of the highly specialised
equipment needed then this is very simply to do via a cheque sent to me
and made payable to Kings College London. If required the contributions
of all significant donors will be acknowledged on the plaque we intend
to mount at the Centre reception.

I believe the creation of this Centre marks an important milestone in
dental research that will provide the basis for the new generation of
biological dental treatments.

Many thanks for your interest.

I look forward to hearing from you.

Yours,

Paul Sharpe

Professor Paul Sharpe
Department of Craniofacial Development
Dental Institute
Kings College London
Floor 28 Guy's Hospital
London Bridge
London
SE1 9RT
UK

Hi Thom,

Thanks for sharing that. Notice that Dr. Sharpe asked the donation be made to the university instead of the company, which adds to the integrity of the project. I hope we can get a tax receipts for the donation. I am sure the university is making them accountable for their expenditures (rent,utilities,salaries etc.)

Thom are you by chance related to the famous Dr. Flemming (he discovered penicillin- and yes he was Canadian!)

Also, if you hear from the company "down under" let us know, I want to read something I can laugh at!

If you have the links to the articles by Dr. Rene please post them.

Sorry I mixed Dr. Flemming with Dr. Frederick Grant Banting who discovered insulin. I think Flemming was a Brit!

here is the link for the pilot human trial i wrote about earlier...
goes to show that human trials would happen in the recent future!!

http://www.window.state.tx.us/txinnovator/ti0506/

Since, I verified the letter, address and speak with a secreyary from the university these funds will be going into a new regenerative dentistry facility...this could hopefully mean they are getting ready for human testing. I donated $100US but please donate what you can and send a letter each time requesting when human trials are to be expected. GOOD LUCK

Fred,
I am going to post every letter you would not believe the lies and excuses they came up with it is totally laughable and what i said to them is more hilarious.

For everyone unaware what we are talking about I found a comany trying to scam money out of us in Australia
www.geneticsolutions.org

They are crooks harrass them, because they are trying to take advantage of victims.

Thom

Hi. Sent my donation and my letter. Thanks for the address.

Hi. Thanks for the address. I sent my donation and letter as soon as you posted the address. Thanks.

Dawn,

You are awesome! I am sure Dr. Sharpe and the university will be pleased that we are trying to make a difference.

Also, I reported these scam artists claiming they could get individuals priority placement in human trials for regrowing teeth after you pay a LARGE deposit. Their site is down as of today, I reported them to the IFCC (International Fraud Consumer Complaint) and they inturn reported them to the FBI. Genetic Solutions is a scam BEWARE if they show their face again. (www.geneticsolutions.org)SCAM SCAM SCAM!!!

Bonjour,

I was reading your post with interest, do you know when human trials on this tooth growth will start. I read that they have also develop alternate filling which helps tooth as it has dentin (I think dentrix site noted this)

It sound like how you say science fiction, can it be true?

Any information on this?

Hi to All, This is a great board and I am so happy to find it .I have been following DR Paul Sharpe's work for a few yearws now and am so excited that I may actually be able to donate and help out. In 2000 I was arial sprayed with 3 seperate chemicals at my home and developed quite severe ostiomylitis and had abcesses and lost many teeth. I went on to see 8 dentiste in US and Canada all who took great amounts of money and made the problem much, much worse..Till finally one day 2.5 years ago I vowed to never see a dentist again and began researching the regeneration of bone and teeth .
Many Blessings to all of us...and may this great work revolutionize dental procedures.

C. A. Bellini

I found this thread a recent while ago and am very excited, but feel the need for urgency. I keep checking this thread to see if something came out that is available or some major breakthrough which would give greater dental technology now instead of the near future.

What is the latest development with the people who are in touch with the Doctor? What is the latest we can expect in the U.S.? I read a post about an injection to prevent cavities, are there any other latest development that will help individuals now or in the near future 6month - 1year.

Research is being conducted aross the world not just in the US. If any treatment does occur it would only be at most a few years extra for it to be available in these countries.

Laser eye surgery is available, and getting better! It will only be time before you you can re-grow teeth, use alternate fillings, etc.

Just think of the radical change to the dental industry, everyone (dental industry) will need additional continuing education courses for this!

It was f