Resveratrol occurs in such low concentrations in wines as compared to the doses used in experiments to tweak sirtuin genes that some scientists suspect that other compounds in wines are delivering the heart healthy benefits claimed for wine consumption. British researchers think the've identified which compounds in wines deliver the biggest benefit and which wines have the most of such compounds.
"The endothelial cells which line our arteries are an important site of action for the vascular protective effects of polyphenols," Roger Corder, of Queen Mary's School of Medicine and Dentistry in London, said in a prepared statement. "We purified the most biologically active polyphenols and identified them as procyanidins."
The researchers then tested wines from two regions in southwest France and Sardinia and compared them with wines from other countries. The wines from France and Sardinia had surprisingly high levels of procyanidins, often five to 10 times more than wines produced elsewhere, the researchers found.
Wines high in tannins are the ticket.
Procyanidins, however, suppressed the synthesis of a peptide called endothelin-1 that constricts blood vessels.
"The traditional production methods used in Sardinia and southwestern France ensure that the beneficial compounds, procyanidins [tannins], are efficiently extracted," says researcher Roger Corder of Queen Mary's William Harvey Research Institute of the University of London, in a news release.
"This may explain the strong association between consumption of traditional tannic wines with overall well-being, reflected in greater longevity," he says.
The winemakers of that region tend to use more traditional techniques in which Tannat grapes are soaked with their seeds longer, boosting the procyanidins.
You could also take pills that contain grape seed extract. Maybe swallowing grape seeds while eating seeded grapes is a good idea?
I'm eating dark chocolate and cranberries to get the same compounds. Walnuts, raspberries, blueberries, apples, and dark grape juice are all good source. I would expect that vintners in other regions could adjust their wine preparation techniques to greatly increase the concentrations of the procyanidins as well.
You have options. Choose a way to get more procyanidins.
|Share |||Randall Parker, 2006 November 29 09:03 PM Aging Diet Studies|