CHICAGO -- Researchers have discovered that even a small amount of MDMA, better known as ecstasy, can be harmful to the brain, according to the first study to look at the neurotoxic effects of low doses of the recreational drug in new ecstasy users. The findings were presented today at the annual meeting of the Radiological Society of North America (RSNA).
“We found a decrease in blood circulation in some areas of the brain in young adults who just started to use ecstasy,” said Maartje de Win, M.D., radiology resident at the Academic Medical Center at the University of Amsterdam in the Netherlands. “In addition, we found a relative decrease in verbal memory performance in ecstasy users compared to non-users.”
Note that Dr. de Win is in the Netherlands and therefore probably not under the control of what some paranoids see as a US government plot to produce lots of false propagandistic drug research which supposedly has corrupted all drug research in America. But who knows. Maybe the CIA does international work for the US National Institute on Drug Absue
Ecstasy is an illegal drug that acts as a stimulant and psychedelic. A 2004 survey by the National Institute on Drug Abuse (NIDA) found that 450,000 people in the United States age 12 and over had used ecstasy in the past 30 days. In 2005, NIDA estimated that 5.4 percent of all American 12th graders had taken the drug at least once.
Ecstasy targets neurons in the brain that use the chemical serotonin to communicate. Serotonin plays an important role in regulating a number of mental processes including mood and memory.
Research has shown that long-term or heavy ecstasy use can damage these neurons and cause depression, anxiety, confusion, difficulty sleeping and decrease in memory. However, no previous studies have looked at the effects of low doses of the drug on first-time users.
So we know that MDMA in longer term users causes damage. But these researchers wanted to find out how quickly the damage appears to show up. So they recruited malleable young minds who were just about to tune in, turn on, and drop out (anyone else remember that drug documentary with Timothy Leary?).
Dr. de Win and colleagues examined 188 volunteers with no history of ecstasy use but at high-risk for first-time ecstasy use in the near future. The examinations included neuroimaging techniques to measure the integrity of cells and blood flow in different areas of the brain and various psychological tests. After 18 months, 59 first-time ecstasy users who had taken six tablets on average and 56 non-users were re-examined with the same techniques and tests.
The ecstasy users experienced decreased blood flow in some brain regions and decreased verbal memory performance.
The study found that low doses of ecstasy did not severely damage the serotonergic neurons or affect mood. However, there were indications of subtle changes in cell architecture and decreased blood flow in some brain regions, suggesting prolonged effects from the drug, including some cell damage. In addition, the results showed a decrease in verbal memory performance among low-dose ecstasy users compared to non-users.
Unless you happen to have the body and face of a Mischa Barton or a Paris Hilton your brain is probably your most valuable asset. Damaging it for transitory kicks does not seem like a wise strategy. Even Mischa and Paris will reduce their earnings potential if they damage their brains. Please Mischa, be careful. You too Jessica Alba.
|Share |||Randall Parker, 2006 December 03 10:41 AM Brain Addiction|