March 07, 2007
120 Cancer Genes Found At Once

DNA sequencing technologies have allowed the Cancer Genome Project scientists to discover 120 genes that contribute to cancer.

The range of mutations that can drive cancer growth could be much wider than thought. An international research effort called the Cancer Genome Project has identified around 120 new genes that contain mutations promoting the disease.

"This is a lot more cancer genes than we expected to find," says Michael Stratton of the Wellcome Trust's Sanger Institute in Cambridge, UK, one of the leaders of the research.

The discovery of a single gene that contributes to cancer used to constitute a big step forward. Not any more. Declining costs for DNA sequencing make possible much bigger searches for cancer promoting mutations.

These scientists focused their attention on enzymes called kinases which are involved in regulating other enzymes and other cellular components. This was done by sequencing a quarter billion letters of DNA.

Scientists at the Wellcome Trust Sanger Institute, where one-third of the human genome was sequenced, have now pioneered decoding the sequence of cancer genomes. They have carried out the broadest survey yet of the human genome in cancer by sequencing more than 250 million letters of DNA code, covering more than 500 genes and 200 cancers.

The continued decline in the cost of DNA sequencing will eventually make the discovery of important mutations (whether harmful or beneficial) incredibly easy. Scientific instrumentation advances are more important than any one biomedical research discovery because the instrumentation advances make the discoveries possible.

Share |      Randall Parker, 2007 March 07 10:54 PM  Biotech Cancer

MORHEUS said at March 8, 2007 11:07 PM:

this news is bascically wortless

anybody can find cancer genes, right from a 1 year student, to a carpenter in his garage u purchase the gene chip,

centrifuge, and die agents, take sample of healthy tisue then cancer tisue and due the test, the software will

higlight the cancer related genes, .

then again they need to do develop the vectors, to activitate deactivite the specific genes ,

what they did is just something that anybody can do in his garage soo basically almost worthelss

then again they still did better then siting home watching tv lets say

Anonymouse said at March 9, 2007 1:44 AM:

I don't think you understood the point of this post, MORHEUS. You basically repeated what Randall Parker said.

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