November 01, 2007
High Blood Sugar Increases Colorectal Cancer Risk

Here's yet another reason to get lots of exercise, control your weight, and eat a low glycemic index and unrefined diet: The higher blood sugar that comes from eating a highly refined diet and from being a couch potato puts you at greater risk of colon cancer.

The glucose levels observed by researchers in the Polyp Prevention Trial, of which this study was a subset analysis, and the levels of exposure that led to the increased risk, were not unusually elevated. Researchers used a glucose concentration of 99 mg/dl as the cut point for the patients in the high group in the study; a fasting blood glucose level between 100 and 125 mg/dl signals pre-diabetes. The levels used in the study are reflective of those in the general U.S. population, therefore it is important to note that even a modest elevation of fasting glucose can affect a patientís risk of colorectal cancer.

Patients who presented with the highest levels of both insulin and glucose had an approximately 50 percent increased risk of colorectal tumor recurrence. The Polyp Prevention Trial found a recurrence for colorectal tumors of 39.6 percent over four years, meaning the recurrence rate in this subset of patients represents a large increase in absolute risk. Patients who had a high concentration of glucose experienced more than 2.4 times increased odds of advanced tumor recurrence. The subjects with the highest glucose concentration also tended to be slightly older and have higher body mass index (BMI) and waist to hip ratios. Additionally, they were more likely to be male, current smokers, a member of a minority group and less likely to have advanced beyond a high school education. For those without a family history of colorectal cancer, researchers observed an even greater risk with elevated concentrations of insulin and glucose compared to the overall study population.

Shift your diet toward vegetables, fruits, beans, and other healthier foods. If you must eat grains then eat whole grains. I realize you know all this. But reminders are helpful.

Share |      Randall Parker, 2007 November 01 05:23 PM  Aging Diet Cancer Studies


Comments
William said at May 4, 2011 7:24 PM:

To help burn calories the blood sugar level needs to be right, plus that and your metabolism need to stay stable throughout the day. Many modern diet plans encourage eating throughout the day to maintain a healthy constant blood sugar and metabolism level.

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