August 24, 2009
Obesity Accelerates Brain Aging?

We really need effective appetite suppression drugs. Obese older people have smaller brains than non-obese old people.

BRAIN regions key to cognition are smaller in older people who are obese compared with their leaner peers, making their brains look up to 16 years older than their true age. As brain shrinkage is linked to dementia, this adds weight to the suspicion that piling on the pounds may up a person's risk of the brain condition.

This latest report supports previous findings. See my post from 2004: Chronic Pain And Obesity Both Cause Brain Damage.

The history of weight loss diets is a history of failure. The vast majority of dieters eventually regain all their lost weight. Anyone have success in losing a lot of weight and keeping it off for years? If so, how'd you do it?

Share |      Randall Parker, 2009 August 24 10:19 PM  Aging Diet Brain Studies

Fat Man said at August 25, 2009 6:38 AM:

They used to tell me that I am fat because I am stupid, but I guess it is really the other way round.

Dex said at August 25, 2009 9:30 AM:

I lost 60 lbs by counting calories - about 4 years ago - and I've kept it off. I'm not terribly vigilant about it now, but if my pants start to get tight in the waistline, I cut back for a few weeks and it's all good again. Simple sugars are the first to get cut, then breads and starchy vegetables. You're hungry, but you accept that that's the price and that it won't kill you to not eat that last 500 calories. It reinforces you when people you haven't seen in years comment and ask how you did it. It amuses you when the people you've met recently think you're naturally slim. It's sustainable and requires no purchase. Online calorie calculators are usually free and pretty accurate. I like the one at

randomperson said at August 26, 2009 6:54 AM:

I lost 110 lbs over 10 months in 2007 (310 down to 200lbs for a 5'10" 43 year old male). I did it through increased exercise (cardio and weight lifting info lifted from web from t-nation site for example) and diet monitoring (due to increased exercise I eat about 2500 calories a day or more depending on exercise level).

I hover between 200 and 205lbs. I maintain by getting 2 to 5 hours of exercise per week, eat the 5 to 7 small meals a day, and only eat cheat meals every week or two(or at significant times like Thanksgiving).

Key for me was developing a working knowledge of exercise and diet (by diet I mean what you eat, not a prescribed eating plan like atkins or ww) effects and weekly weight-taking & waist measurements. With the weekly measurements I don't drift far off track. I make all my meals in advance (on Sunday's for a week) except for Saturday's dinner, which tends to be a social event.

I do read exercise sites and such to keep up with developements. I don't use any suppliments execept fish oil & protein powder. I eat lots of veggies and fruit (11 to 13 servings perday) and have a high protein diet (about 200 grams a day).

I have a computer desk job and am lazy so it can be done, for me it is just a matter of discipline.

Lono said at August 26, 2009 8:32 AM:

Excellent work people!

I think now, more than ever, it is important for those of us in the intellectual elite to seriously maintain a healthy athleticism to protect our natural gifts.

(especially since so many of us have unnatural desk jobs pouring over computers for most of the day)

The way society is going - and as we approach the singularity - more and more will the citizens of every nation on Earth turn and look to us, their intellectual superiors, for real and strong leadership!

Let us all be well prepared for the Next Renaissance!

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