December 07, 2009
Lymphoma Progression Linked To Low Vitamin D

Another reason to make sure you get enough vitamin D.

ROCHESTER, Minn. A new study has found that the amount of vitamin D (http://www.mayoclinic.org/news2008-mchi/4904.html) in patients being treated for diffuse large B-cell lymphoma (http://www.mayoclinic.org/non-hodgkins-lymphoma/)was strongly associated with cancer progression and overall survival. The results will be presented at the annual meeting of the American Society of Hematology (http://www.hematology.org/) in New Orleans.

"These are some of the strongest findings yet between vitamin D and cancer outcome," says the study's lead investigator, Matthew Drake, M.D., Ph.D., (http://www.mayoclinic.org/bio/13726218.html) an endocrinologist at Mayo Clinic in Rochester. "While these findings are very provocative, they are preliminary and need to be validated in other studies. However, they raise the issue of whether vitamin D supplementation might aid in treatment for this malignancy, and thus should stimulate much more research."

The researchers' study of 374 newly diagnosed diffuse large B-cell lymphoma patients found that 50 percent had deficient vitamin D levels based on the commonly used clinical value of total serum 25(OH)D less than 25 ng/mL. Patients with deficient vitamin D levels had a 1.5-fold greater risk of disease progression and a twofold greater risk of dying, compared to patients with optimal vitamin D levels after accounting for other patient factors associated with worse outcomes.

It is winter time in the Northern Hemisphere. Your risk of vitamin D deficiency is greatest in the darker months. Many studies find a link between vitamin D deficiency and increased cancer risk. Here's another such study.

Share |      Randall Parker, 2009 December 07 05:55 AM  Aging Diet Cancer Studies


Comments
Paul said at December 7, 2009 8:16 AM:

My wife had a rash on her leg. The dermatologist ran a bunch of tests for various things (some quite alarming) and diagnosed vitamin D deficiency. I had been telling her for years about all the results linking low D to various ailments. We're all drinking more milk and taking vitamin D supplements now.

Eric Johnson said at December 7, 2009 11:12 PM:

There have been interventional studies for a few years already. What we really need is more of the latter. Why an observational trial? He should have just pumped half the deficient people full of D.

Not that I'm not taking D based on what is known already. I take at least 2000 IU a day on average. Its the only thing I take besides omega3s

Peter said at December 8, 2009 1:39 PM:

Gotta love the standard line:

"While these findings are very provocative, they are preliminary and need to be validated in other studies."

Is there ever a point where researchers don't call for "further studies?"

Doug Collins said at December 8, 2009 2:45 PM:

Is there ever a point where researchers don't call for "further studies?"


Yeah. When the "Science is settled"

Narniaman said at December 8, 2009 3:00 PM:

"they are preliminary and need to be validated in other studies"

means. . . . .

"We need a whole bunch more money to produce more papers like this and for me to pad my resume."

NikFromNYC said at December 8, 2009 3:41 PM:

Vitamin D is a small pill and one of the cheapest you can buy and its not merely an anti-oxidant (for which it's best to take a very large variety in quite small doses). Omega-3, if you want the best (distilled) is rather expensive.

Ugh...why do you have a FORGET PERSONAL INFORMATION button?

Bob Badour said at December 10, 2009 8:05 AM:

One would have to take a hell of a lot of it to get toxicity:
http://dietary-supplements.info.nih.gov/factsheets/vitamind.asp#h8

I take 2000 IU a day.

Kryptview A780 said at February 16, 2011 1:08 AM:

Vitamin D is obtained from skin exposure to sunlight,from certain foods and from supplements.I don't feel anything from it,but like Chris once said, you can't feel not getting cancer.Cancer researchers have discovered that vitamin D regulates a number of genes in various cancers,including prostate, colon and breast cancers.

Flooring said at February 17, 2011 8:16 PM:

Vitamins are necessary for our body it helps in growing our body part.Vitamin D is very helpful for our body parts.Defficiency of vitamin D may cause many problems.You share so nice article on this it is so impressive information.

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