February 23, 2011
Higher Vitamin D Needed For Disease Risk Reduction

A survey of several thousand volunteers taking a wide range of vitamin D supplement doses finds substantial disease risk reduction at 4000-8000 IU per day. More than I take. Hmmm...

Researchers at the University of California, San Diego School of Medicine and Creighton University School of Medicine in Omaha have reported that markedly higher intake of vitamin D is needed to reach blood levels that can prevent or markedly cut the incidence of breast cancer and several other major diseases than had been originally thought. The findings are published February 21 in the journal Anticancer Research

While these levels are higher than traditional intakes, they are largely in a range deemed safe for daily use in a December 2010 report from the National Academy of Sciences Institute of Medicine.

Among the diseases whose risks appear to be cut in half by higher D: breast cancer, colon cancer, multiple sclerosis, and type 1 diabetes.

"We found that daily intakes of vitamin D by adults in the range of 4000-8000 IU are needed to maintain blood levels of vitamin D metabolites in the range needed to reduce by about half the risk of several diseases - breast cancer, colon cancer, multiple sclerosis, and type 1 diabetes," said Cedric Garland, DrPH, professor of family and preventive medicine at UC San Diego Moores Cancer Center. "I was surprised to find that the intakes required to maintain vitamin D status for disease prevention were so high much higher than the minimal intake of vitamin D of 400 IU/day that was needed to defeat rickets in the 20th century."

One could get one's blood tested for vitamin D and adjust upward on dose and get retested until one reaches the 40 to 60 ng/ml blood level this study suggests is needed for optimal benefit.

Share |      Randall Parker, 2011 February 23 12:28 AM  Aging Diet Studies

Nick G said at February 23, 2011 10:03 AM:

I take 5,000 per day, and that only gets me to the bottom end of the range! I've seen several anecdotal reports of the same experience.

Mirco Romanato said at February 28, 2011 8:27 PM:

The problem is with the intake of Vit A. The two vitamins are at odd one with the other. So higher Vit A cause lower Vit D and the reverse is true.
I take a shot of 300.000 UI of Vit.D every two months, beat to eat it daily.

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