September 03, 2011
Exercise Tells Stem Cells To Become Bone, Not Fat

Tell all your mouse friends. Yet another reason for mice to get on that treadmill and run like mad.

HAMILTON Sept. 1, 2011 McMaster researchers have found one more reason to exercise: working out triggers influential stem cells to become bone instead of fat, improving overall health by boosting the body's capacity to make blood.

The body's mesenchymal stem cells are most likely to become fat or bone, depending on which path they follow.

Using treadmill-conditioned mice, a team led by the Department of Kinesiology's Gianni Parise has shown that aerobic exercise triggers those cells to become bone more often than fat.

The exercising mice ran less than an hour, three times a week, enough time to have a significant impact on their blood production, says Parise, an associate professor.

Does this result apply to humans? Probably. So the next time a dog tries to get you to go running take his advice. He's obviously up on the scientific research on exercise.

Share |      Randall Parker, 2011 September 03 07:12 PM  Aging Exercise Studies


Comments
PacRim Jim said at September 4, 2011 11:49 AM:

Everyone knows what is good for them. Why do you suppose we don't do it?
Have our memes outrun our genes in the race for survival?

Doug said at September 4, 2011 2:05 PM:

Bravo, Randall. Interesting, important, and immediately useful. I'll nominate this one for post of the month.

Porkov said at September 4, 2011 3:45 PM:

How can we chase women if they refuse to run away?

bbartlog said at September 5, 2011 8:09 AM:

@PacRimJim: for the ten million years preceding the last two hundred or so, conserving energy to ward off eventual starvation was a top priority. The resulting tendencies to laziness are still written all over our genetic code.

Lou Pagnucco said at September 7, 2011 10:14 AM:

Perhaps of interest is the just published news release -
"Scientists discover switch that turns white fat brown"
http://medicalxpress.com/news/2011-09-scientists-white-fat-brown.html

It appears that (at least in mice) enriched environments lead to a conversion of energy-storing white fat cells into energy-consuming metabolically active brown fat, possibly by generating brain-derived neurotrophic factor (BDNF) - independent of exercise.

BTW, several berries (bilberries, blueberries,...) are reported to both increase BDNF as well as preventing the differentiation of stem cells into fat cells. So would exercise and dietary berries have synergistic effects?


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