May 25, 2013
Anticholinergic Drugs Cause Cognitive Impairment In 60 Days

Hey, can I get your attention? If I can't get your attention you might just be on an anticholinergic drug.

INDIANAPOLIS -- Research from the Regenstrief Institute, the Indiana University Center for Aging Research and Wishard-Eskenazi Health on medications commonly taken by older adults has found that drugs with strong anticholinergic effects cause cognitive impairment when taken continuously for as few as 60 days. A similar impact can be seen with 90 days of continuous use when taking multiple drugs with weak anticholinergic effect.

Using a sleeping pill or antihistamine?

The Regenstrief Institute, IU Center for Aging Research and Wishard-Eskenazi Health researchers reported that continuously taking strong anticholinergics, like many sleeping pills or antihistamines, for only 60 days caused memory problems and other indicators of mild cognitive impairment. Taking multiple drugs with weaker anticholinergic effects, such as many common over-the-counter digestive aids, had a negative impact on cognition in 90 days.

On any of these long term? Benadryl, Sominex, Advil PM, Dramamine, Zyban, Wellbutrin and other anti-cholinergics listed on that page.

Share |      Randall Parker, 2013 May 25 09:14 PM 

Lono said at May 28, 2013 12:29 PM:

I saw my girl get straight stupid after round' 60+ days on Wellbutrin... I put the kibosh on that right quick. Since then all she's needed is a daily dose of the D to keep her happy and well adjusted.

(True Story)

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