June 17, 2013
Antidepressants Behind Obesity Epidemic?

Rats living stressed lives and taking fluoxetine (a.k.a Prozac or Sarafem) undergo long term increases in body weight.

SAN FRANCISCO—- Short-term use of antidepressants, combined with stress and a high-fat diet, is associated with long-term increases in body weight, a new animal study finds. The results were presented Sunday at The Endocrine Society's 95th Annual Meeting in San Francisco.

"Our study suggests that short-term exposure to stress and antidepressants, rather than a high-calorie, high-fat diet alone, leads to long-term body weight gain, accompanied with increased bone and spleen weights," said study lead author Suhyun Lee, a PhD candidate in the medical sciences at the John Curtin School of Medical Research at the Australian National University in Canberra, Australia.

What I would like to know: how much has too much evening blue light exposure from computers and house lights lowered melatonin production, reduced sleep, and therefore made people more prone to depression? Then antidepressants could just amount to a piling on where they increase obesity even more than lack of sleep does.

Anyone wear UV-blocking glasses in the evening to sleep better? I'm a pretty good sleeper. But blocking blue light in the evening might prevent slow creep toward later times to go to sleep and wake up.

Share |      Randall Parker, 2013 June 17 09:32 PM 

Begira said at June 19, 2013 3:53 PM:

We need antidepressants that cause less weight gain. Wellbutrin is one but ideally they'd find an SSRI that didn't cause weight gain.

Natalie Imbru said at June 20, 2013 5:45 PM:

We need depressed people to live in a village in the amazon,in situ if you like, (funded and build by a company like Astra zeneca),and then those people to be used as trial subjects for all the millions and billions of plants with the potential to cure their illness. Obviously AI is being used to sift through all the potential molecules with potential to alleviate affliction,but a super-computer lacks the human touch!The most mind-blowing psycoactive drug i have ever tried,Ibogaine, isn't even artificial! (it can stop any addiction in a few hours).
Nw i am surfing FP in internet cafes in Europe, and in places like London and Milan i keep the Futurepundit page open to encourage more of the plebs to appreciate Randall Parker.

Brett Bellmore said at June 26, 2013 2:28 PM:

Are lab animals on strictly controlled diets getting anti-depressants? There seems to be some general phenomenon effecting all mammalian life. Maybe a virus, or a common gut symbiont.

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