Obese but with low blood pressure and good lipid profile? Healthy Obesity does not exist. That is from a meta study by Canadian researchers. Some researchers in Texas published similar findings a couple of weeks ago: The damage is being done.
"Unfortunately, our findings suggest metabolically healthy obesity is not a benign condition," said the study's corresponding author, Carlos Lorenzo, MD, of the University of Texas Health Science Center at San Antonio, Texas. "Regardless of their current metabolic health, people who are obese face an increased risk of developing cardiovascular disease and diabetes in the future."
Researchers analyzed prospective data from the San Antonio Heart Study, a population-based study of Mexican Americans and Caucasians, to assess incidence of diabetes in 2,814 participants and cardiovascular disease incidence in 3,700 participants. The SAHS study followed up with participants for a period lasting between six and 10 years. The analysis examined whether the risk of developing diabetes or heart disease was different for normal weight people who had at least two metabolic conditions or metabolically healthy obese people.
What would be the effect of wearing 50 pounds of weights outside your body as you go thru life? Probably beneficial on net. Though maybe more joint injuries. But fat tissue releases lots of hormones into the blood. In particular one hormone released by adipose tissue causes the liver to produce too much glucose. This leads to type 2 diabetes.
The ability of one organ—in this case, the adipose tissue—to so directly and profoundly control the actions of another—the liver —is in itself very exciting, said Hotamisligil. "We suspect this communication system between adipose tissue and liver may have evolved to help fat cells command the liver to supply the body with glucose in times of nutrient deprivation. However, when the engorged fat cells lose control over this signal in obesity, the blood levels of aP2 rise, glucose is poured into the bloodstream and cannot be cleared by other tissues. The result is high blood glucose levels and type 2 diabetes.
We need some great biotechnology for regulating appetite.
|Share |||Randall Parker, 2013 December 02 08:31 PM|