2008 February 26 Tuesday
Cats Cut Heart Attack Risk?

Fluffy warms your heart and keeps it beating.

Owning a cat could reduce your risk of a heart attack by nearly one third, researchers told delegates of the American Stroke Association's International Stroke Conference in New Orleans last week. The finding provoked a mixed reaction from heart experts and veterinarians.

The finding was the main result of a 10 year study of more than 4,000 Americans by researchers at the University of Minnesota's Stroke Institute in Minneapolis. Executive director of the Institute, Dr Adnan Qureshi, who is also senior author of the study, was reported by US News & World Report to have said:

The study didn't include enough dog owners to prove a benefit from dogs. My suspicion is that dogs reduce heart attack risk as well - especially dogs whose owners let the dogs become personal trainers. A big Australian Shepherd Red Merle named Oakley did more to make me exercise than any hobby or person ever did.

This study probably tells us that a lot of people feel a fair amount of stress. If cats cut our heart risks they probably do this my making us feel more relaxed. Well, if that is the case a lot of people are killing themselves with worry. What to do about it? Try living below your means. Then a job loss or unexpected expenses will cause less stress.

By Randall Parker    2008 February 26 08:47 PM   Entry Permalink | Comments ( 2 )
2008 January 08 Tuesday
Sun Exposure Causes Net Reduction In Cancer Risk

Scientists at U.S. Department of Energy's Brookhaven National Laboratory and colleagues in Norway have found evidence that the increased risk of melanoma cancer from sun exposure is outweighed by reduced risk of internal cancers as a result of increased vitamin D production.

In the current study, Setlow and his colleagues used a model incorporating information on solar radiation intensity and a vertical cylinder shape to represent the human body's skin surface to calculate the relative production of vitamin D via sunlight as a function of latitude, or distance from the equator. The cylindrical model more realistically represents human body sun exposure than flat surface exposure measurements used in previous models. The scientists also examined the incidence of and survival rates for various forms of cancer by latitude.

According to the calculations, people residing in Australia (just below the equator) produce 3.4 times more vitamin D as a result of sun exposure than people in the United Kingdom, and 4.8 times more than people in Scandinavia.

"There is a clear north-south gradient in vitamin D production," Setlow says, "with people in the northern latitudes producing significantly less than people nearer the equator."

In populations with similar skin types, there is also a clear increase in the incidence of all forms of skin cancer from north to south. "This gradient in skin cancer rates indicates that there is a true north-south gradient in real sun exposure," Setlow says.

The scientists also found that the incidence rates of major internal cancers such as colon cancer, lung cancer, and cancers of the breast and prostate also increased from north to south. However, when the scientists examined the survival rates for these cancers, they found that people from the southern latitudes were significantly less likely to die from these internal cancers than people in the north.

Since melanoma is caused by UVA radiation but vitamin D synthesis is caused by UVB radiation the scientists suggest that sun screens should selectively filter out the UVA in order to give the best of both worlds: no higher melanoma risk combined with lower internal cancer risk.

By Randall Parker    2008 January 08 11:26 PM   Entry Permalink | Comments ( 1 )
4 Factors Add 14 Years To Life Expectancy

Want to live longer? Don't smoke. Eat 5 servings of vegetables and fruits daily. Get moderate exercise. Drink between 1 and 14 glasses of wine or half pints of beer per week. A study of over 25,000 people in Norfolk county UK published in Plos Medicine found that people who smoke, do not get enough fruits and vegetables, do not get enough exercise, and do not drink moderately die 14 years sooner on average than people who are the opposite on these lifestyle characteristics.

What Did the Researchers Do and Find?

Between 1993 and 1997, about 20,000 men and women aged 45–79 living in Norfolk UK, none of whom had cancer or cardiovascular disease (heart or circulation problems), completed a health and lifestyle questionnaire, had a health examination, and had their blood vitamin C level measured as part of the EPIC-Norfolk study. A health behavior score of between 0 and 4 was calculated for each participant by giving one point for each of the following healthy behaviors: current non-smoking, not physically inactive (physical inactivity was defined as having a sedentary job and doing no recreational exercise), moderate alcohol intake (1–14 units a week; a unit of alcohol is half a pint of beer, a glass of wine, or a shot of spirit), and a blood vitamin C level consistent with a fruit and vegetable intake of at least five servings a day. Deaths among the participants were then recorded until 2006. After allowing for other factors that might have affected their likelihood of dying (for example, age), people with a health behavior score of 0 were four times as likely to have died (in particular, from cardiovascular disease) than those with a score of 4. People with a score of 2 were twice as likely to have died.

What Do These Findings Mean?

These findings indicate that the combination of four simply defined health behaviors predicts a 4-fold difference in the risk of dying over an average period of 11 years for middle-aged and older people. They also show that the risk of death (particularly from cardiovascular disease) decreases as the number of positive health behaviors increase. Finally, they can be used to calculate that a person with a health score of 0 has the same risk of dying as a person with a health score of 4 who is 14 years older.

A Danish study also published today found the same benefits from moderate alcohol and moderate exercise in over 11,000 Danes.

People who drink moderate amounts of alcohol and are physically active have a lower risk of death from heart disease and other causes than people who don’t drink at all, according to new research. People who neither drink alcohol nor exercise have a 30-49 per cent higher risk of heart disease than those who either drink, exercise or both.

The research, which was published in the European Heart Journal [1] today (Wednesday 9 January), is the first to look at the combined influence of leisure-time physical activity and weekly alcohol intake on the risk of fatal ischaemic heart disease (a form of heart disease characterised by a reduced blood supply to the heart) and deaths from all causes.

Between 1981-1983 Danish researchers obtained information on various health-related issues (including exercise and alcohol intake) from 11,914 Danish men and women aged 20 or older, who were taking part in the larger, Copenhagen City Heart Study.

Want to do more? Add some fish for an added health benefit. Eat even more than 5 servings of fruits and vegetables per day and some nuts too. Also, reduce your red meat consumption and lower your dietary glycemic index.

By Randall Parker    2008 January 08 10:55 PM   Entry Permalink | Comments ( 6 )
2008 January 01 Tuesday
Lack Of Sleep Lowers Insulin Sensitivity

Getting your high quality deep sleep interrupted might put you at greater risk of insulin insensitive type 2 diabetes.

Suppression of slow-wave sleep in healthy young adults significantly decreases their ability to regulate blood-sugar levels and increases the risk of type 2 diabetes, report researchers at the University of Chicago Medical Center in the “Early Edition” of the Proceedings of the National Academy of Science, available online as soon as Dec. 31, 2007.

Deep sleep, also called “slow-wave sleep,” is thought to be the most restorative sleep stage, but its significance for physical well-being has not been demonstrated. This study found that after only three nights of selective slow-wave sleep suppression, young healthy subjects became less sensitive to insulin. Although they needed more insulin to dispose of the same amount of glucose, their insulin secretion did not increase to compensate for the reduced sensitivity, resulting in reduced tolerance to glucose and increased risk for type 2 diabetes. The decrease in insulin sensitivity was comparable to that caused by gaining 20 to 30 pounds.

Previous studies have demonstrated that reduced sleep quantity can impair glucose metabolism and appetite regulation resulting in increased risk of obesity and diabetes. This current study provides the first evidence linking poor sleep quality to increased diabetes risk.

"These findings demonstrate a clear role for slow-wave sleep in maintaining normal glucose control," said the study's lead author, Esra Tasali, MD, assistant professor of medicine at the University of Chicago Medical Center. "A profound decrease in slow-wave sleep had an immediate and significant adverse effect on insulin sensitivity and glucose tolerance."

Get your sleep or lose control of your glucose. You have a decision to make. Don't be a chump. Stay in control.

We get less deep sleep as we get older. That decay in sleep quality might contribute to the rise in the incidence of type 2 diabetes as we age.

“Since reduced amounts of deep sleep are typical of aging and of common obesity-related sleep disorders, such as obstructive sleep apnea these results suggest that strategies to improve sleep quality, as well as quantity, may help to prevent or delay the onset of type 2 diabetes in populations at risk,” said Eve Van Cauter, PhD, professor of medicine at the University of Chicago and senior author of the study.

So many processes of aging create a vicious cycle. Your sleep quality deteriorates. Then your glucose levels go to high. That accelerates your aging and that makes your sleep quality even worse. The cycle repeats. We need rejuvenation therapies that will break this vicious cycle. We need to stop the downward spiral.

By Randall Parker    2008 January 01 10:41 PM   Entry Permalink | Comments ( 0 )
2007 September 24 Monday
Skimping On Sleep Increases Death Risk

Skimping on the sleep might kill you.

Researchers from the University of Warwick, and University College London, have found that lack of sleep can more than double the risk of death from cardiovascular disease. However they have also found that point comes when too much sleep can also more than double the risk of death.

In research to be presented on Monday 24th September 2007, to the British Sleep Society, Professor Francesco Cappuccio from the University of Warwick’s Warwick Medical School  will show the results of a study of how sleep patterns affected the mortality of 10,308  civil servants in the “Whitehall II study”. Amongst other things the data they used provided information on the mortality rates and sleep patterns on the same group of civil servants at two points in their life (1985-8 and those still alive in 1992-3).

The researchers took into account other possible factors such age, sex, marital status, employment grade, smoking status, physical activity, alcohol consumption, self-rated health, body mass index, blood pressure, cholesterol, other physical illness etc. Once they had adjusted for those factors they were able to isolate the effect that changes in sleep patterns over 5 years had on mortality rates 11-17 years later.

Taking those who had not made any change in their sleeping habits between 1985-8 and 1992-3  as their baseline (7 hours per night being the figure normally recommended as an appropriate period of sleep for an adult) they were able to see what difference having reduced the amount of sleep over time  made to mortality rates by 2004.

Those who had cut their sleeping from 7h to 5 hours or less faced a 1.7 fold increased risk in mortality from all causes, and twice the increased risk of death from a cardiovascular problem in particular.

People who sleep less could conceivably have diseases that are disrupting their sleep and eventually killing them. But that seems an unlikely explanation given the stress effects of sleep deprivation. Get enough sleep. It ight save your life.

By Randall Parker    2007 September 24 11:14 PM   Entry Permalink | Comments ( 1 )
2007 September 09 Sunday
Lack Of Sleep Creates High Blood Pressure Risk For Women

Women especially should try to get enough sleep.

The University of Warwick led research team looked at data from "The Whitehall II Cohort" which studied volunteers from 20 London-based civil service departments. There were a total of 6,592 participants (4,199 men and 1,567 women). The Warwick team defined hypertension as blood pressure equal to or higher than 140/90 mm Hg or if the subject made regular use of antihypertensive medications.

The researchers found that the those women in the study group who slept less than or equal to 5 hours a night were twice as likely to suffer from hypertension than women who slept for the more recommended seven hours or more a night. The researchers found no difference between men sleeping less than 5 hours and those sleeping 7 hours or more.

I wonder if the difference is due a difference in how male and female bodies react to sleep deficits. Or maybe the conditions that cause women to sleep less are different than the conditions that make men sleep less. Maybe stressful environments cause women to miss sleep but for men maybe the sleep is missed due to the desire to do more activities that are less stressful. Mind you, that's pure speculation. More likely female bodies react to lack of sleep in ways that do more damage to blood vessels.

Whether you are a man or women there are plenty of scientific reasons why you should get enough sleep. See my previous posts Less Sleep Increases Obesity, Sleep A Lot To Avoid Burn-Out From Stress And To Stay Skinny, and Lack Of Sleep Suppresses Neurogenesis And Memory Formation. Sleep is good.

By Randall Parker    2007 September 09 04:15 PM   Entry Permalink | Comments ( 1 )
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